Development of innovative biomaterials and devices for the treatment of cardiovascular diseases

Y Wang, G Li, L Yang, R Luo, G Guo - Advanced Materials, 2022 - Wiley Online Library
Cardiovascular diseases have become the leading cause of death worldwide. The
increasing burden of cardiovascular diseases has become a major public health problem …

Advances in drug delivery via electrospun and electrosprayed nanomaterials

M Zamani, MP Prabhakaran… - International journal of …, 2013 - Taylor & Francis
Electrohydrodynamic (EHD) techniques refer to procedures that utilize electrostatic forces to
fabricate fibers or particles of different shapes with sizes in the nano-range to a few microns …

The effect of thick fibers and large pores of electrospun poly (ε-caprolactone) vascular grafts on macrophage polarization and arterial regeneration

Z Wang, Y Cui, J Wang, X Yang, Y Wu, K Wang, X Gao… - Biomaterials, 2014 - Elsevier
The vascular grafts prepared by electrospinning often have relatively small pores, which limit
cell infiltration into the grafts and hinder the regeneration and remodeling of the grafts into …

Long term performance of polycaprolactone vascular grafts in a rat abdominal aorta replacement model

S de Valence, JC Tille, D Mugnai, W Mrowczynski… - Biomaterials, 2012 - Elsevier
In the active field of vascular graft research, polycaprolactone is often used because of its
good mechanical strength and its biocompatibility. It is easily processed into micro and nano …

Mechanically reinforced biotubes for arterial replacement and arteriovenous grafting inspired by architectural engineering

D Zhi, Q Cheng, AC Midgley, Q Zhang, T Wei, Y Li… - Science …, 2022 - science.org
There is a lack in clinically-suitable vascular grafts. Biotubes, prepared using in vivo tissue
engineering, show potential for vascular regeneration. However, their mechanical strength is …

Tissue‐engineered vascular grafts: emerging trends and technologies

P Gupta, BB Mandal - Advanced Functional Materials, 2021 - Wiley Online Library
Vascular tissue engineering has made prodigious progress in recent years by converging
multidisciplinary approaches. Latest technological advancements foster the development of …

Electrospun cellular microenvironments: Understanding controlled release and scaffold structure

A Szentivanyi, T Chakradeo, H Zernetsch… - Advanced drug delivery …, 2011 - Elsevier
Electrospinning is a versatile technique in tissue engineering for the production of scaffolds.
To guide tissue development, scaffolds must provide specific biochemical, structural and …

[HTML][HTML] Development of drug loaded cardiovascular prosthesis for thrombosis prevention using 3D printing

J Domínguez-Robles, T Shen, VA Cornelius… - Materials Science and …, 2021 - Elsevier
Cardiovascular disease (CVD) is a general term for conditions which are the leading cause
of death in the world. Quick restoration of tissue perfusion is a key factor to combat these …

Influence of the fiber diameter and surface roughness of electrospun vascular grafts on blood activation

V Milleret, T Hefti, H Hall, V Vogel, D Eberli - Acta biomaterialia, 2012 - Elsevier
Electrospun grafts have been widely investigated for vascular graft replacement due to their
ease and compatibility with many natural and synthetic polymers. Here, the effect of the …

In Vivo Applications of Electrospun Tissue-Engineered Vascular Grafts: A Review

KA Rocco, MW Maxfield, CA Best, EW Dean… - … Engineering Part B …, 2014 - liebertpub.com
There is great clinical demand for synthetic vascular grafts with improved long-term efficacy.
The ideal vascular conduit is easily implanted, nonthrombogenic, biocompatible, resists …