TLR2 and TLR4 mediated host immune responses in major infectious diseases: a review

S Mukherjee, S Karmakar, SPS Babu - Brazilian Journal of Infectious …, 2016 - SciELO Brasil
During the course of evolution, multicellular organisms have been orchestrated with an
efficient and versatile immune system to counteract diverse group of pathogenic organisms …

Natural products are a promising source for anthelmintic drug discovery

KLTD Jayawardene, EA Palombo, PR Boag - Biomolecules, 2021 - mdpi.com
Parasitic nematodes infect almost all forms of life. In the human context, parasites are one of
the major causative factors for physical and intellectual growth retardation in the developing …

Anthelmintics in the future: current trends in the discovery and development of new drugs against gastrointestinal nematodes

M Zajíčková, LT Nguyen, L Skálová, LR Stuchlíková… - Drug Discovery …, 2020 - Elsevier
Highlights•Gastrointestinal nematodes are resistant to available anthelmintics.•No new
anthelmintic on the market for several years.•A target-based approach, drug repurposing or …

Plant-based natural products for the discovery and development of novel anthelmintics against nematodes

M Liu, SK Panda, W Luyten - Biomolecules, 2020 - mdpi.com
Intestinal parasitic nematodes infect approximately two billion people worldwide. In the
absence of vaccines for human intestinal nematodes, control of infections currently relies …

[HTML][HTML] Preliminary analysis of phytoconstituents and evaluation of anthelminthic property of Cayratia auriculata (in vitro)

N Kancherla, A Dhakshinamoothi, K Chitra… - Maedica, 2019 - ncbi.nlm.nih.gov
Context: Phytoconstituents of medicinal plants have been playing a key role in treating
various diseases all over the world since ancient times. The present study was focused on …

[HTML][HTML] Herbal anthelmintic agents: a narrative review

A Manjusa, K Pradeep - Journal of Traditional Chinese Medicine, 2022 - ncbi.nlm.nih.gov
Helminths or Parasitic worms of humans may cause chronic and sometimes deadly
diseases, considered as neglected tropical diseases (NTDs) that infect around two billion …

Amino-acid-conjugated natural compounds: aims, designs and results

H Arifian, R Maharani, S Megantara, AM Gazzali… - Molecules, 2022 - mdpi.com
Protein is one of the essential macronutrients required by all living things. The breakdown of
protein produces monomers known as amino acids. The concept of conjugating natural …

An inventory of anthelmintic plants across the globe

H Ahmed, SG Kilinc, F Celik, HK Kesik, S Simsek… - Pathogens, 2023 - mdpi.com
A wide range of novelties and significant developments in the field of veterinary science to
treat helminth parasites by using natural plant products have been assessed in recent years …

Natural products as anthelmintics: safeguarding animal health

AA Salim, MS Butler, MAT Blaskovich… - Natural Product …, 2023 - pubs.rsc.org
Covering literature to December 2022 This review provides a comprehensive account of all
natural products (500 compounds, including 17 semi-synthetic derivatives) described in the …

The Antiviral Potential of Perilla frutescens: Advances and Perspectives

J Chen, Y Zhao, J Cheng, H Wang, S Pan, Y Liu - Molecules, 2024 - pmc.ncbi.nlm.nih.gov
Viruses pose a significant threat to human health, causing widespread diseases and
impacting the global economy. Perilla frutescens, a traditional medicine and food …