Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins
Q Yu, Z Wang, Y Tu, Y Cao, H Zhu, J Shao… - Bioorganic …, 2024 - Elsevier
Intrinsically disordered proteins (IDPs) are characterized by their inability to adopt well-
defined tertiary structures under physiological conditions. Nonetheless, they often play …
defined tertiary structures under physiological conditions. Nonetheless, they often play …
Rpt5-Derived Analogs Stimulate Human Proteasome Activity in Cells and Degrade Proteins Forming Toxic Aggregates in Age-Related Diseases
K Cekała, K Trepczyk, J Witkowska… - International Journal of …, 2024 - mdpi.com
Aging and age-related diseases are associated with a decline in the capacity of protein
turnover. Intrinsically disordered proteins, as well as proteins misfolded and oxidatively …
turnover. Intrinsically disordered proteins, as well as proteins misfolded and oxidatively …
[PDF][PDF] Peptydy i peptydomimetyki wywodzące się z białek Rpt5 i Blm10 jako stymulatory ludzkiego proteasomu 20S in vitro i in cellulo
K Cekała - bip.ug.edu.pl
Stosowane w tekście skróty i symbole aminokwasów oraz grup ochronnych są zgodne z
zaleceniami IUPAC-IUB Joint Commision on Biochemical Nomenclature, Nomenclature and …
zaleceniami IUPAC-IUB Joint Commision on Biochemical Nomenclature, Nomenclature and …