Treatment strategies for infected wounds

I Negut, V Grumezescu, AM Grumezescu - Molecules, 2018 - mdpi.com
The treatment of skin wounds is a key research domain owing to the important functional
and aesthetic role of this tissue. When the skin is impaired, bacteria can soon infiltrate into …

[HTML][HTML] The microbiome in patients with atopic dermatitis

AS Paller, HH Kong, P Seed, S Naik… - Journal of Allergy and …, 2019 - Elsevier
As an interface with the environment, the skin is a complex ecosystem colonized by many
microorganisms that coexist in an established balance. The cutaneous microbiome inhibits …

Human wounds and its burden: an updated compendium of estimates

CK Sen - Advances in wound care, 2019 - liebertpub.com
Significance: A 2018 retrospective analysis of Medicare beneficiaries identified that∼ 8.2
million people had wounds with or without infections. Medicare cost estimates for acute and …

Mining for encrypted peptide antibiotics in the human proteome

MDT Torres, MCR Melo, L Flowers… - Nature Biomedical …, 2022 - nature.com
The emergence of drug-resistant bacteria calls for the discovery of new antibiotics. Yet, for
decades, traditional discovery strategies have not yielded new classes of antimicrobial …

Atopic dermatitis: Role of the skin barrier, environment, microbiome, and therapeutic agents

T Luger, M Amagai, B Dreno, MA Dagnelie… - Journal of …, 2021 - Elsevier
Atopic dermatitis (AD) is a chronic, inflammatory skin disorder characterized by eczematous
and pruritic skin lesions. In recent decades, the prevalence of AD has increased worldwide …

[HTML][HTML] Modeling microbial abundances and dysbiosis with beta-binomial regression

BD Martin, D Witten, AD Willis - The annals of applied statistics, 2020 - ncbi.nlm.nih.gov
Using a sample from a population to estimate the proportion of the population with a certain
category label is a broadly important problem. In the context of microbiome studies, this …

The cutaneous microbiome and wounds: new molecular targets to promote wound healing

TR Johnson, BI Gómez, MK McIntyre… - International journal of …, 2018 - mdpi.com
The ecological community of microorganisms in/on humans, termed the microbiome, is vital
for sustaining homeostasis. While culture-independent techniques have revealed the role of …

[图书][B] A clinical guide to the treatment of the human stress response

SG Everly, M Lating Jr - 2019 - Springer
A Clinical Guide to the Treatment of the Human Stress Response Page 1 George S. Everly,
Jr. · Jeffrey M. Lating A Clinical Guide to the Treatment of the Human Stress Response …

3D skin models for 3R research: The potential of 3D reconstructed skin models to study skin barrier function

H Niehues, JA Bouwstra, A El Ghalbzouri… - Experimental …, 2018 - Wiley Online Library
The skin barrier is an important shield regulating the outside‐in as well as inside‐out
penetration of water, nutrients, ions and environmental stimuli. We can distinguish four …

Diagnosis and treatment of xerosis cutis–a position paper

M Augustin, D Wilsmann‐Theis… - JDDG: Journal der …, 2019 - Wiley Online Library
Background and rationale Xerosis cutis (also referred to as xeroderma, dry skin, asteatosis)
affects more than 10 million individuals in Germany. It is among the most common …