Cutaneous squamous cell carcinoma: a review of high-risk and metastatic disease

KA Burton, KA Ashack, A Khachemoune - American journal of clinical …, 2016 - Springer
Non-melanoma skin cancer represents one-third of all malignancies and its incidence is
expected to rise until the year 2040. Cutaneous squamous cell carcinoma (cSCC) …

Epidermal growth factor receptor (EGFR) and squamous cell carcinoma of the skin: molecular bases for EGFR-targeted therapy

P Uribe, S Gonzalez - Pathology-Research and Practice, 2011 - Elsevier
Cutaneous squamous cell carcinoma (SCC) ranks second in the frequency of all skin
tumors. Its incidence has risen significantly due to an increased sun exposure and the …

Genomic analysis of metastatic cutaneous squamous cell carcinoma

YY Li, GJ Hanna, AC Laga, RI Haddad, JH Lorch… - Clinical cancer …, 2015 - AACR
Purpose: A rare 5% of cutaneous squamous cell carcinomas (cSCC) metastasize, lack FDA-
approved therapies, and carry a poor prognosis. Our aim was to identify recurrent genomic …

Eyelid and ocular surface carcinoma: diagnosis and management

VT Yin, HA Merritt, M Sniegowski, B Esmaeli - Clinics in dermatology, 2015 - Elsevier
Eyelid cancers account for 5% to 10% of all cutaneous malignancies. The incidence of
eyelid cancer is approximately 15 cases per 100,000 individuals per year. Basal cell …

Mechanisms of resistance to HER family targeting antibodies

TJ Kruser, DL Wheeler - Experimental cell research, 2010 - Elsevier
The epidermal growth factor (EGF) family of receptor tyrosine kinases consists of four
members: EGFR (HER1/ErbB1), HER2/neu (ErbB2), HER3 (ErbB3) and HER4 (ErbB4) …

Epidermal growth factor receptor expression is associated with poor outcome in cutaneous squamous cell carcinoma

J Cañueto, E Cardeñoso, JL García… - British Journal of …, 2017 - academic.oup.com
Background Cutaneous squamous cell carcinoma (CSCC) is the second most frequent
cancer in humans after basal cell carcinoma, and its incidence is dramatically rising. CSCC …

Treatment of unresectable and metastatic cutaneous squamous cell carcinoma

LD Cranmer, C Engelhardt, SS Morgan - The oncologist, 2010 - academic.oup.com
Cutaneous squamous cell carcinoma (SCC) is an already common disorder with a rapidly
increasing incidence. Treatment of early disease depends primarily on surgery or …

Aggressive cutaneous squamous cell carcinoma of the head and neck: a review

N Desai, MK Divatia, A Jadhav, A Wagh - Current Oncology, 2023 - mdpi.com
Non-melanoma skin cancer of the head and neck (NMSCHN) is one of the most common
malignancies worldwide, and its incidence is growing at a significant rate. It has been found …

Targeted therapy for orbital and periocular basal cell carcinoma and squamous cell carcinoma

VT Yin, ML Pfeiffer, B Esmaeli - Ophthalmic Plastic & …, 2013 - journals.lww.com
Purpose: To review the literature on targeted therapy for orbital and periocular basal cell
carcinoma (BCC) and cutaneous squamous cell carcinoma (SCC) and provide examples of …

Cutaneous squamous cell carcinoma of the head and neck metastasizing to the parotid gland—a review of current recommendations

J O'Hara, A Ferlito, RP Takes, A Rinaldo… - Head & …, 2011 - Wiley Online Library
Cutaneous squamous cell carcinoma (SCC) of the head and neck may metastasize in up to
5% of patients, with the parotid lymph nodes the most frequent site for spread. Metastases …