Nanotherapeutics demonstrate poor accumulation in the tumor microenvironment due to
poor extravasation and penetration into the tumor. Therapeutics such as oligonucleotides …

Chylothorax is a rare cause of pleural effusion, secondary to accumulation of lymph in the
pleural space. Diagnosis is based on the triglyceride and cholesterol content of pleural fluid …

Abstract Aims The Fontan operation has resulted in improved survival in patients with single‐
ventricle congenital heart disease. As a result, there is a growing population of teenagers …

Background Microvascular dysfunction plays an important role in the pathogenesis of heart
failure with preserved ejection fraction (HFpEF). However, no mechanistic link between …

Abstract Purpose of Review Lymphatic disorders have received an increasing amount of
attention over the last decade. Sparked primarily by improved imaging modalities and the …

Background: Lymphatic embolization therapy has proven effective for Fontan failure from
plastic bronchitis or protein-losing enteropathy but not when multiple lymphatic …

The lymphatic vasculature has traditionally been considered important for removal of
excessive fluid from the interstitial space, absorption of fat from the intestine and the immune …

Congenital heart disease can lead to notable lymphatic complications such as chylothorax,
plastic bronchitis, protein-losing enteropathy, and ascites. Recent improvements in …

Fontan-type surgery is the final step in the sequential palliative surgical treatment of infants
born with a univentricular heart. The resulting long-term haemodynamic changes promote …

The lymphatics play important roles in chronic diseases/conditions that comprise the bulk of
healthcare worldwide. Yet the ability to routinely image and diagnose lymphatic dysfunction …