Respiratory syncytial virus (RSV) is amongst the most important pathogenic infections of
childhood and is associated with significant morbidity and mortality. Although there have …

The early stages of life are associated with increased susceptibility to infection, which is in
part due to an ineffective immune system. In the context of infection, the immune system …

The mammalian gastrointestinal tract harbors a complex ecosystem consisting of countless
bacteria in homeostasis with the host immune system. Shaped by evolution, this partnership …

Allergic rhinitis is clinically defined as a symptomatic disorder of the nose induced by an IgE-
mediated inflammation after allergen exposure of the membranes lining the nose. Symptoms …

Although we might shudder at the thought of billions of bacteria living in our lower intestine,
we are colonized by these passengers shortly after birth. However, the relationship is mostly …

We have a mutually beneficial relationship with the trillions of microorganisms inhabiting our
gastrointestinal tract. However, maintaining this relationship requires recognizing these …

Background: Improved hygiene has altered early microbial exposure by reducing childhood
infections, which has been suggested as a cause for the continuously rising prevalence of …

Allergic rhinitis, asthma, and atopic eczema are among the commonest causes of chronic ill
health. These diseases are increasing in prevalence, and they add considerably to the …

Advances in metagenomics, proteomics, metabolomics, and systems biology are providing a
new emphasis in research; interdisciplinary work suggests that personalized medicine is on …

The past decade has brought great strides in our understanding of adaptive immunity in
neonatal mice. Although poor immune responses are commonly observed, it is now clear …