Cancer is known as one of the main causes of death in the world; and many compounds
have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile …

Oncological diseases have currently reached an epidemic scale, especially in industrialized
countries. Such a situation has prompted complex studies in medicinal chemistry focused on …

Pyrazole derivatives, as a class of heterocyclic compounds, possess unique chemical
structures that confer them with a broad spectrum of pharmacological activities. They have …

As part of our effort to identify potent α‐amylase inhibitors, in the present study, a novel
series of fluorinated thiazolidinone‐pyrazole hybrid molecules were prepared by the …

Coumarin hybrids have been designed and synthesized as an important new strategy in the
field of medicinal chemistry. Coumarin core has been shown to form various compounds to …

New hydrazonoyl-sulfonylthiazoles were designed and synthesized as EGFR inhibitors. The
new sulfonylthiazole derivatives were assessed in vitro to measure their effect on EGFR …

Bacterial resistance to antibiotics threatens our progress in healthcare, modern medicine,
food production and ultimately life expectancy. Antibiotic resistance is a global concern …

MRSA infection is one of the alarming diseases in the current scenario. Identifying newer
molecules to treat MRSA infection is of urgent need. In the present study, we have designed …

Over the past few decades, a significant number of anticancer drugs have been developed,
both natural and synthetic. Thiazole, a 5-membered distinctive heterocyclic motif with …

Two new series of pyrazolyl-thiazolidinone/thiazole derivatives 16a–b and 18a–j were
synthesised, merging the scaffolds of celecoxib and dasatinib. Compounds 16a, 16b and 18f …