Periodontal disease is classically characterized by progressive destruction of the soft and
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …

Oral and esophageal squamous cell carcinomas harbor a diverse microbiome that differs
compositionally from precancerous and healthy tissues. Though causality is yet to be …

Mounting evidence from metagenomic analyses suggests that a state of pathological
microbial imbalance or dysbiosis is prevalent in the gut of patients with colorectal cancer …

Periodontitis is characterized by a chronic inflammation produced in response to a disease‐
associated multispecies bacterial community in the subgingival region. Although the …

Alveolar bone is a unique osseous tissue due to the proximity of dental plaque biofilms.
Periodontal health and homeostasis are mediated by a balanced host immune response to …

Extensive research in humans and animal models has begun to unravel the complex
mechanisms that drive the immunopathogenesis of periodontitis. Neutrophils mount an early …

Increasing evidence suggests a significant association between periodontal disease and the
occurrence of various cancers. The carcinogenic potential of several periodontal pathogens …

Chronic bone degenerative diseases represent a major threat to the health and well-being
of the population, particularly those with advanced age. This study isolated exosomes …

Periodontitis is the most common chronic, inflammatory oral disease that affects more than
half of the population in the United States. The disease leads to destruction of the tooth …

Rheumatoid arthritis (RA) is a systemic immune mediated inflammatory disease of unknown
origin, which is predominantly affecting the joints. Antibodies against citrullinated peptides …