Within the broad spectrum of atrial fibrillation (AF) symptomatology, there is a striking subset
of patients with predominant or even solitary nocturnal onset of the arrhythmia. This review …

BACKGROUND: Ventricular arrhythmias (VAs) demonstrate a prominent day-night rhythm,
commonly presenting in the morning. Transcriptional rhythms in cardiac ion channels …

Aim Cardiac arrhythmias and sudden deaths have diurnal rhythms in humans. The
underlying mechanisms are unknown. Mice with cardiomyocyte‐specific disruption of the …

Abstract Aim Heart Failure with preserved Ejection Fraction (HFpEF) is characterized by
diastolic dysfunction and reduced cardiac output, but its pathophysiology remains poorly …

Background: Cardiac gene expression and arrhythmia occurrence have time-of-day
variation; however, daily changes in cardiac electrophysiology, arrhythmia susceptibility …

Abstract Kruppel-like factor 15 (KLF15) is a subtype of the Kruppel-like family of transcription
factors (KLFs). KLFs have three high-fidelity zinc fingers at the carboxyl terminus that enable …

Sudden cardiac arrest is a malfunction of the heart's electrical system, typically caused by
ventricular arrhythmias, that can lead to sudden cardiac death (SCD) within minutes …

Chronic kidney disease (CKD) and uremia increase the risk of heart disease and sudden
cardiac death. Coronary artery disease can only partly account for this. The remaining …

Aim Cardiovascular complications, including cardiac arrhythmias, result in high morbidity
and mortality in patients with type‐2 diabetes mellitus (T2DM). Clinical and experimental …

Background. In addition to show autonomous beating rhythmicity, the physiological functions
of the heart present daily periodic oscillations. Notably the ventricular repolarization itself …