Morphological, mechanical, and biological evolution of pure hydroxyapatite and its composites with titanium carbide for biomedical applications

SK Avinashi, P Singh, K Sharma, A Hussain… - Ceramics …, 2022 - Elsevier
Pure hydroxyapatite (HAp) was synthesized successfully via a wet chemical precipitation
method. To study the influence of TiC (weight% of 5, 10, 15) substitution on the mechanical …

Enhanced physical and mechanical properties of resin added with aluminum oxyhydroxide for dental applications

S Kumari, A Hussain, SK Avinashi, RK Mishra… - Ceramics …, 2023 - Elsevier
Resin has limited applications however, its composites with metal oxides exhibited improved
characteristics for numerous applications such as dental restoration, dentures etc. Herein …

Chebulinic acid alleviates LPS-induced inflammatory bone loss by targeting the crosstalk between reactive oxygen species/NFκB signaling in osteoblast cells

K Sharma, S Kumar, R Prakash, S Khanka… - Free Radical Biology …, 2023 - Elsevier
Chebulinic acid (CA), a plant ellagitannin derived from Triphala, is reported to exhibit both
anti-inflammatory & anti-oxidant activity apart from anti-tumour property. However, its role in …

Cladrin alleviates dexamethasone-induced apoptosis of osteoblasts and promotes bone formation through autophagy induction via AMPK/mTOR signaling

R Rai, KB Singh, S Khanka, R Maurya… - Free Radical Biology and …, 2022 - Elsevier
Glucocorticoid-induced osteoporosis (GIOP) is a common clinical consequence that arises
due to the extensive usage of glucocorticoids. Cladrin (Clad), a methoxylated isoflavone has …

Maintenance of increased bone mass after PTH withdrawal by sequential medicarpin treatment via augmentation of cAMP‐PKA pathway

K Sharma, P Awasthi, R Prakash… - Journal of Cellular …, 2022 - Wiley Online Library
Osteoporosis is a metabolic bone disorder associated with impaired bone microarchitecture
leading to fragility fractures. Long‐term usage of parathyroid hormone (PTH) enhances bone …

山奈酚活性单体治疗骨质疏松症的相关信号通路

杨启培, 陈锋, 崔伟, 张驰, 武瑞骐, 宋振恒, 孟鑫 - 中国组织工程研究, 2024 - cjter.com
山奈酚活性单体治疗骨质疏松症的相关信号通路 Page 1 4242|中国组织工程研究|第28卷|第26期
|2024年9月 中国组织工程研究 Chinese Journal of Tissue Engineering Research www.CJTER.com …

Bone Fracture-healing Properties and UPLC-MS Analysis of an Enriched Flavonoid Fraction from Oxystelma esculentum

P Rawat, K Sharma, S Khanka, Y Singh… - Planta …, 2024 - thieme-connect.com
Oxystelma esculentum has been used as a folk medicine to treat jaundice, throat infections,
and skin problems. In the current study, the bone fracture-healing properties of a flavonoid …

3-PEP promotes bone regeneration by up regulating BCL-2 expression via ERK phosphorylation

A Tripathi, P Awasthi, KS Rawat… - Journal of …, 2022 - joe.bioscientifica.com
Bone healing and regeneration is a complex process that recapitulates embryonic skeletal
development and is delayed in diseases like osteoporosis. Bone healing therapies like …

Signaling pathways related to kaempferol active monomers in the treatment of osteoporosis

Q Yang, F Chen, W Cui, C Zhang, R Wu, Z Song… - Chinese Journal of …, 2024 - cjter.com
BACKGROUND: Recent studies have shown that the occurrence and prevention of
osteoporosis often focus on the cellular molecular level, and the mechanism of related …