Gut microbiota profiling: metabolomics based approach to unravel compounds affecting human health
P Vernocchi, F Del Chierico, L Putignani - Frontiers in microbiology, 2016 - frontiersin.org
The gut microbiota is composed of a huge number of different bacteria, that produce a large
amount of compounds playing a key role in microbe selection and in the construction of a …
amount of compounds playing a key role in microbe selection and in the construction of a …
1H NMR-based metabolite profiling for biomarker identification
RA Silva, TCS Pereira, AR Souza, PR Ribeiro - Clinica Chimica Acta, 2020 - Elsevier
The metabolome is affected by individual physiologic and pathophysiologic states as well as
the environment. Metabolomics has become crucial approach for clinical studies, providing …
the environment. Metabolomics has become crucial approach for clinical studies, providing …
Multi-dimensional metabolomic profiling reveals dysregulated ornithine metabolism hallmarks associated with a severe acute pancreatitis phenotype
J Yang, N Shi, S Wang, M Wang, Y Huang, Y Wang… - Translational …, 2024 - Elsevier
To reveal dysregulated metabolism hallmark that was associated with a severe acute
pancreatitis (SAP) phenotype. In this study, LC-MS/MS-based targeted metabolomics was …
pancreatitis (SAP) phenotype. In this study, LC-MS/MS-based targeted metabolomics was …
Quantitative metabolic analysis of plasma extracellular vesicles for the diagnosis of severe acute pancreatitis
Background Severe acute pancreatitis (SAP) is the most common gastrointestinal disease
and is associated with unpredictable seizures and high mortality rates. Despite …
and is associated with unpredictable seizures and high mortality rates. Despite …
[HTML][HTML] Metabolomic-based clinical studies and murine models for acute pancreatitis disease: A review
Acute pancreatitis (AP) is one of the most common gastroenterological disorders requiring
hospitalization and is associated with substantial morbidity and mortality. Metabolomics …
hospitalization and is associated with substantial morbidity and mortality. Metabolomics …
Serum concentrations of citrate, tyrosine, 2-and 3-hydroxybutyrate are associated with increased 3-month mortality in acute heart failure patients
Considering the already established relationship between the extent of the metabolic
dysfunction and the severity of heart failure (HF), it is conceivable that the metabolomic …
dysfunction and the severity of heart failure (HF), it is conceivable that the metabolomic …
Intestinal microflora and metabolites affect the progression of acute pancreatitis (AP)
Z Wang, M Guo, S Yang, Y Chen, J Cheng, Z Huang… - Gut Pathogens, 2024 - Springer
Specific intestinal metabolites are closely associated with the classification, severity, and
necrosis of acute pancreatitis (AP) and provide novel insights for in-depth clinical …
necrosis of acute pancreatitis (AP) and provide novel insights for in-depth clinical …
[HTML][HTML] NMR spectroscopy as a “green analytical method” in metabolomics and proteomics studies
KA Mielko, N Pudełko-Malik, A Tarczewska… - Sustainable Chemistry …, 2021 - Elsevier
Nuclear magnetic resonance (NMR) is one of two methods (in addition to MS) that
predominate in metabolomics and structural analysis. Due to the great demand for this type …
predominate in metabolomics and structural analysis. Due to the great demand for this type …
Plasmatic oxidative and metabonomic profile of patients with different degrees of biliary acute pancreatitis severity
P Silva-Vaz, I Jarak, L Rato, PF Oliveira… - Antioxidants, 2021 - mdpi.com
Acute pancreatitis (AP) is an inflammatory process of the pancreas with variable involvement
of the pancreatic and peripancreatic tissues and remote organ systems. The main goal of …
of the pancreatic and peripancreatic tissues and remote organ systems. The main goal of …
Identification of potential diagnostic biomarkers of acute pancreatitis by serum metabolomic profiles
H Xiao, J Huang, X Zhang, R Ahmed, Q Xie, B Li, Y Zhu… - Pancreatology, 2017 - Elsevier
Acute pancreatitis (AP) is defined as an acute inflammation of pancreas that may cause
damage to other tissues and organs depending upon the severity of symptoms. The …
damage to other tissues and organs depending upon the severity of symptoms. The …