Asymmetric catalysis mediated by synthetic peptides, version 2.0: expansion of scope and mechanisms

AJ Metrano, AJ Chinn, CR Shugrue, EA Stone… - Chemical …, 2020 - ACS Publications
Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

Catalytic asymmetric synthesis of butenolides and butyrolactones

B Mao, M Fañanás-Mastral, BL Feringa - Chemical reviews, 2017 - ACS Publications
γ-Butenolides, γ-butyrolactones, and derivatives, especially in enantiomerically pure form,
constitute the structural core of numerous natural products which display an impressive …

Enantioselective copper-catalyzed conjugate addition and allylic substitution reactions

A Alexakis, JE Backvall, N Krause, O Pàmies… - Chemical …, 2008 - ACS Publications
In the past decades there has been a dramatic increase in the demand for enantiopure
compounds for fine-chemicals (ie, agrochemicals and pharmaceuticals) and material …

Catalytic asymmetric conjugate addition and allylic alkylation with Grignard reagents

SR Harutyunyan, T den Hartog, K Geurts… - Chemical …, 2008 - ACS Publications
Catalytic asymmetric CC bond-forming reactions using organometallic reagents are among
the most important of organic transformations. 1 Frequently, these transformations are key …

Asymmetric synthesis of tertiary alcohols and α-tertiary amines via Cu-catalyzed C− C bond formation to ketones and ketimines

M Shibasaki, M Kanai - Chemical reviews, 2008 - ACS Publications
Chiral tertiary alcohols and R-tertiary amines are important building blocks of naturally
occurring and artificial biologically active molecules. Although there are catalytic asymmetric …

Recent advances in enantioselective copper-catalyzed 1, 4-addition

T Jerphagnon, MG Pizzuti, AJ Minnaard… - Chemical Society …, 2009 - pubs.rsc.org
A comprehensive overview of recent literature from 2003 concerning advances in
enantioselective copper catalysed 1, 4-addition of organometallic reagents to α, β …

[HTML][HTML] Evolution in heterodonor PN, PS and PO chiral ligands for preparing efficient catalysts for asymmetric catalysis. From design to applications

J Margalef, M Biosca, P de la Cruz Sanchez… - Coordination Chemistry …, 2021 - Elsevier
The success of phosphine-oxazoline ligands (PHOX) inspired the progress in P-oxazoline
ligand families by modifying either the ligand backbone, the electronic and/or steric …

Evolution of catalytic stereoselective olefin metathesis: from ancillary transformation to purveyor of stereochemical identity

AH Hoveyda - The Journal of organic chemistry, 2014 - ACS Publications
There have been numerous significant advances in catalytic olefin metathesis (OM) during
the past two decades. Such progress has transformed this important set of reactions to …

Catalytic enantioselective synthesis of flavanones and chromanones

MM Biddle, M Lin, KA Scheidt - Journal of the American Chemical …, 2007 - ACS Publications
The enantioselective synthesis of flavanones and chromanones is described. Bifunctional
thiourea catalysts promote an asymmetric oxo-conjugate addition to a β-ketoester alkylidene …

Dual-function cinchona alkaloid catalysis: catalytic asymmetric tandem conjugate addition− protonation for the direct creation of nonadjacent stereocenters

Y Wang, X Liu, L Deng - Journal of the American Chemical …, 2006 - ACS Publications
Catalytic tandem asymmetric reactions constitute a powerful strategy for the asymmetric
construction of nonadjacent stereocenters in acyclic molecules directly from achiral …