Pathogen-imposed selection pressures have been paramount during human evolution.
Detecting such selection signatures in ancient and modern human genomes can thus help …

The sequencing of ancient DNA from archaic humans—Neanderthals and Denisovans—has
revealed that modern and archaic humans interbred at least twice during the Pleistocene …

Humans have undergone large migrations over the past hundreds to thousands of years,
exposing ourselves to new environments and selective pressures. Yet, evidence of ongoing …

Admixture has been a pervasive phenomenon in human history, extensively shaping the
patterns of population genetic diversity. There is increasing evidence to suggest that …

Over the past 50 years, geneticists have made great strides in understanding how our
species' evolutionary history gave rise to current patterns of human genetic diversity …

Background Human population history in the Holocene was profoundly impacted by
changes in lifestyle following the invention and adoption of food-production practices. These …

Gene flow between previously differentiated populations during the founding of an admixed
or hybrid population has the potential to introduce adaptive alleles into the new population. If …

Genetic variation and susceptibility to disease are shaped by human demographic history
and adaptation. We can now study the genomes of extant Africans and uncover traces of …

Immune response is one of the functions that have been more strongly targeted by natural
selection during human evolution. The evolutionary genetic dissection of the immune system …

Central Africa, a forested region that supports an exceptionally high biodiversity, hosts the
world's largest group of hunter-gatherers, who live in close proximity with groups that have …