The belief that the vertebrate brain functions normally without classical lymphatic drainage
vessels has been held for many decades. On the contrary, new findings show that functional …

Subarachnoid hemorrhage (SAH) has a high mortality rate and causes long-term disability
in many patients, often associated with cognitive impairment. However, the pathogenesis of …

Although recent technical advances in thrombectomy have revolutionised acute stroke
treatment, prevalence of disability and death related to stroke remain high. Therefore …

Haemoglobin is released into the CNS during the breakdown of red blood cells after
intracranial bleeding. Extracellular free haemoglobin is directly neurotoxic. Haemoglobin …

Pharmacological interventions have been tested experimentally and clinically to prevent
hydrocephalus and avoid the need for shunting beginning in the 1950s. Clinical trials of …

Abstract Post-hemorrhagic hydrocephalus (PHH), also referred to as progressive ventricular
dilatation, is caused by disturbances in cerebrospinal fluid (CSF) flow or absorption …

Immunologic changes in the hematoma of patients with intracerebral hemorrhage (ICH) and
the contribution of these changes to prognosis are unknown. We collected the blood …

We investigated cerebrospinal fluid (CSF) expression of inflammatory cytokines and their
relationship with spontaneous intracerebral and intraventricular hemorrhage (ICH, IVH) and …

Collagen-type I alpha 1 chain (COL1A1) and COL1A2 are abnormally expressed in
intracranial aneurysm (IA), but their mechanism of action remains unclear. This study was …

Objective: To investigate the temporal pattern and relevant associations of CSF inflammatory
measures after intraventricular hemorrhage (IVH). Methods: We analyzed prospectively …