Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease characterised by
worsening respiratory symptoms and physiological impairment. Increasing awareness of the …

Hypersensitivity pneumonitis (HP) is a complex syndrome caused by the inhalation of a
variety of antigens in susceptible and sensitized individuals. These antigens are found in the …

Background Many people recovering from coronavirus disease 2019 (COVID-19)
experience prolonged symptoms, particularly breathlessness. We urgently need to identify …

Background Preclinical data have suggested that nintedanib, an intracellular inhibitor of
tyrosine kinases, inhibits processes involved in the progression of lung fibrosis. Although the …

Objective To analyze the efficacy and safety of nintedanib in patients with fibrosing
autoimmune disease–related interstitial lung diseases (ILDs) with a progressive phenotype …

600 patients aged≥ 18 years will be randomised in a 1: 1 ratio to nintedanib or placebo.
Patients with diagnosis of IPF will be excluded. The study population will be enriched with …

Background In fibrotic interstitial lung diseases, exertional breathlessness is strongly linked
to health-related quality of life (HRQOL). Breathlessness is often associated with oxygen …

Background: Patients with serious respiratory illness and their caregivers suffer
considerable burdens, and palliative care is a fundamental right for anyone who needs it …

In some patients, respiratory symptoms and imaging abnormalities persist after acute
coronavirus disease 2019 (COVID-19) pneumonia [1–3]. Chest computed tomography (CT) …

Abstract Background The INSIGHTS-IPF registry provides one of the largest data sets of
clinical data and self-reported patient related outcomes including health related quality of life …