Acupuncture for pain management: molecular mechanisms of action
T Chen, WW Zhang, YX Chu… - The American journal of …, 2020 - World Scientific
Acupuncture reduces pain by activating specific areas called acupoints on the patient's
body. When these acupoints are fully activated, sensations of soreness, numbness, fullness …
body. When these acupoints are fully activated, sensations of soreness, numbness, fullness …
[HTML][HTML] The mechanistic basis for the effects of electroacupuncture on neuropathic pain within the central nervous system
M Zhou, Q Zhang, M Huo, H Song, H Chang… - Biomedicine & …, 2023 - Elsevier
Nociceptive signaling responses to painful stimuli are transmitted to the central nervous
system (CNS) from the afferent nerves of the periphery through a series of neurotransmitters …
system (CNS) from the afferent nerves of the periphery through a series of neurotransmitters …
[HTML][HTML] Potential mechanisms of acupuncture for neuropathic pain based on somatosensory system
X Ma, W Chen, NN Yang, L Wang, XW Hao… - Frontiers in …, 2022 - frontiersin.org
Neuropathic pain, caused by a lesion or disease of the somatosensory system, is common
and distressing. In view of the high human and economic burden, more effective treatment …
and distressing. In view of the high human and economic burden, more effective treatment …
The Role of Neuroglial Crosstalk and Synaptic Plasticity‐Mediated Central Sensitization in Acupuncture Analgesia
Z Lyu, Y Guo, Y Gong, W Fan, B Dou, N Li… - Neural …, 2021 - Wiley Online Library
Although pain is regarded as a global public health priority, analgesic therapy remains a
significant challenge. Pain is a hypersensitivity state caused by peripheral and central …
significant challenge. Pain is a hypersensitivity state caused by peripheral and central …
[HTML][HTML] Role of nerve signal transduction and neuroimmune crosstalk in mediating the analgesic effects of acupuncture for neuropathic pain
Y Chen, D Li, N Li, PY Loh, Y Guo, X Hu… - Frontiers in …, 2023 - frontiersin.org
Neurogenic pain rises because of nervous system damage or dysfunction and is the most
difficult to treat among other pathological pains. Acupuncture has been reported as a great …
difficult to treat among other pathological pains. Acupuncture has been reported as a great …
[HTML][HTML] Electroacupuncture modulates spinal BDNF/TrκB signaling pathway and ameliorates the sensitization of dorsal horn WDR neurons in spared nerve injury rats
M Xue, YL Sun, YY Xia, ZH Huang, C Huang… - International Journal of …, 2020 - mdpi.com
Neuropathic pain is more complex and severely affects the quality of patients' life. However,
the therapeutic strategy for neuropathic pain in the clinic is still limited. Previously we have …
the therapeutic strategy for neuropathic pain in the clinic is still limited. Previously we have …
Electroacupuncture treatment attenuates paclitaxel-induced neuropathic pain in rats via inhibiting spinal glia and the TLR4/NF-κB pathway
YX Zhao, MJ Yao, Q Liu, JJ Xin, JH Gao… - Journal of pain …, 2020 - Taylor & Francis
Background and Purpose Neuropathic pain is a major side-effect of paclitaxel (PTX)
chemotherapy. Although the precise mechanisms responsible for this pain are unclear, the …
chemotherapy. Although the precise mechanisms responsible for this pain are unclear, the …
[HTML][HTML] Electroacupuncture improves neuronal plasticity through the A2AR/cAMP/PKA signaling pathway in SNL rats
Q Wu, J Chen, J Yue, X Ying, Y Zhou, X Chen… - Neurochemistry …, 2021 - Elsevier
Improvements in neuronal plasticity are considered to be conducive to recovery from
neuropathic pain. Electroacupuncture (EA) is regarded as an effective rehabilitation method …
neuropathic pain. Electroacupuncture (EA) is regarded as an effective rehabilitation method …
Effects of acupuncture on neuropathic pain induced by spinal cord injury: a systematic review and meta‐analysis
K He, R Hu, Y Huang, B Qiu, Q Chen… - Evidence‐Based …, 2022 - Wiley Online Library
Introduction. Neuropathic pain is a commonly seen symptom and one of the most intractable
comorbidities following spinal cord injury (SCI). Acupuncture has been widely used for …
comorbidities following spinal cord injury (SCI). Acupuncture has been widely used for …
[HTML][HTML] Electroacupuncture promoted nerve repair after peripheral nerve injury by regulating miR-1b and its target brain-derived neurotrophic factor
YP Liu, Z Luo, C Wang, H Cai, T Zhao, H Li… - Frontiers in …, 2020 - frontiersin.org
Growing evidence indicates that electroacupuncture (EA) has a definite effect on the
treatment of peripheral nerve injury (PNI), but its mechanism is not completely clear …
treatment of peripheral nerve injury (PNI), but its mechanism is not completely clear …