[HTML][HTML] Role of S100 proteins in health and disease
LL Gonzalez, K Garrie, MD Turner - Biochimica et Biophysica Acta (BBA) …, 2020 - Elsevier
The S100 family of proteins contains 25 known members that share a high degree of
sequence and structural similarity. However, only a limited number of family members have …
sequence and structural similarity. However, only a limited number of family members have …
Cellular and molecular mechanisms of allergic asthma
Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …
worldwide. It is the most common chronic disease in children, affecting at least 30 million …
S100 proteins as an important regulator of macrophage inflammation
C Xia, Z Braunstein, AC Toomey, J Zhong… - Frontiers in …, 2018 - frontiersin.org
The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of
intracellular and extracellular functions through regulating calcium balance, cell apoptosis …
intracellular and extracellular functions through regulating calcium balance, cell apoptosis …
Functions of S100 proteins
The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …
All the “RAGE” in lung disease: The receptor for advanced glycation endproducts (RAGE) is a major mediator of pulmonary inflammatory responses
EA Oczypok, TN Perkins, TD Oury - Paediatric respiratory reviews, 2017 - Elsevier
The receptor for advanced glycation endproducts (RAGE) is a pro-inflammatory pattern
recognition receptor (PRR) that has been implicated in the pathogenesis of numerous …
recognition receptor (PRR) that has been implicated in the pathogenesis of numerous …
Nutritional immunity: S100 proteins at the host-pathogen interface
The S100 family of EF-hand calcium (Ca 2+)-binding proteins is essential for a wide range of
cellular functions. During infection, certain S100 proteins act as damage-associated …
cellular functions. During infection, certain S100 proteins act as damage-associated …
Inflammation-associated S100 proteins: new mechanisms that regulate function
J Goyette, CL Geczy - Amino acids, 2011 - Springer
This review focuses on new aspects of extracellular roles of the calgranulins. S100A8,
S100A9 and S100A12 are constitutively expressed in neutrophils and induced in several …
S100A9 and S100A12 are constitutively expressed in neutrophils and induced in several …
Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies
Background Childhood-onset and adult-onset asthma differ with respect to severity and
comorbidities. Whether they also differ with respect to genetic risk factors has not been …
comorbidities. Whether they also differ with respect to genetic risk factors has not been …
Inflammatory bowel disease biomarkers
Inflammatory bowel disease (IBD) is characterized as chronic inflammation in the
gastrointestinal tract, which includes two main subtypes, Crohn's disease and ulcerative …
gastrointestinal tract, which includes two main subtypes, Crohn's disease and ulcerative …
Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease
N Ferhani, S Letuve, A Kozhich… - American journal of …, 2010 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by airway
inflammation and remodeling. High-mobility group box 1 (HMGB1), a nuclear protein that is …
inflammation and remodeling. High-mobility group box 1 (HMGB1), a nuclear protein that is …