Reaction Mechanisms in Carbohydrate-Active Enzymes: Glycoside Hydrolases and Glycosyltransferases. Insights from ab Initio Quantum Mechanics/Molecular …
A Ardèvol, C Rovira - Journal of the American Chemical Society, 2015 - ACS Publications
Carbohydrate-active enzymes such as glycoside hydrolases (GHs) and glycosyltransferases
(GTs) are of growing importance as drug targets. The development of efficient competitive …
(GTs) are of growing importance as drug targets. The development of efficient competitive …
Thermostable enzymes as biocatalysts in the biofuel industry
Lignocellulose is the most abundant carbohydrate source in nature and represents an ideal
renewable energy source. Thermostable enzymes that hydrolyze lignocellulose to its …
renewable energy source. Thermostable enzymes that hydrolyze lignocellulose to its …
Conformational analyses of the reaction coordinate of glycosidases
The enzymatic hydrolysis of the glycosidic bond is catalyzed by diverse enzymes generically
termed glycoside hydrolases (hereafter GHs) or glycosidases. The many sequence-based …
termed glycoside hydrolases (hereafter GHs) or glycosidases. The many sequence-based …
Biotransformation of ginsenosides by hydrolyzing the sugar moieties of ginsenosides using microbial glycosidases
CS Park, MH Yoo, KH Noh, DK Oh - Applied microbiology and …, 2010 - Springer
Ginsenosides are the principal components responsible for the pharmaceutical activities of
ginseng. The minor ginsenosides, which are also pharmaceutically active, can be produced …
ginseng. The minor ginsenosides, which are also pharmaceutically active, can be produced …
β-Xylosidases and α-l-arabinofuranosidases: accessory enzymes for arabinoxylan degradation
S Lagaert, A Pollet, CM Courtin, G Volckaert - Biotechnology advances, 2014 - Elsevier
Arabinoxylan (AX) is among the most abundant hemicelluloses on earth and one of the
major components of feedstocks that are currently investigated as a source for advanced …
major components of feedstocks that are currently investigated as a source for advanced …
How sugars pucker: electronic structure calculations map the kinetic landscape of five biologically paramount monosaccharides and their implications for enzymatic …
HB Mayes, LJ Broadbelt… - Journal of the American …, 2014 - ACS Publications
Glycoside hydrolases (GHs) distort carbohydrate ring geometry along particular “catalytic
itineraries” during the cleavage of glycosidic bonds, illustrating the relationship between …
itineraries” during the cleavage of glycosidic bonds, illustrating the relationship between …
The structure of an inverting GH43 β-xylosidase from Geobacillus stearothermophilus with its substrate reveals the role of the three catalytic residues
C Brüx, A Ben-David, D Shallom-Shezifi, M Leon… - Journal of molecular …, 2006 - Elsevier
β-d-Xylosidases are glycoside hydrolases that catalyze the release of xylose units from short
xylooligosaccharides and are engaged in the final breakdown of plant cell-wall …
xylooligosaccharides and are engaged in the final breakdown of plant cell-wall …
Characterization of the Pseudomonas aeruginosa glycoside hydrolase PslG reveals that its levels are critical for Psl polysaccharide biosynthesis and biofilm formation
A key component of colonization, biofilm formation, and protection of the opportunistic
human pathogen Pseudomonas aeruginosa is the biosynthesis of the exopolysaccharide …
human pathogen Pseudomonas aeruginosa is the biosynthesis of the exopolysaccharide …
β-Xylosidases: Structural diversity, catalytic mechanism, and inhibition by monosaccharides
Xylan, a prominent component of cellulosic biomass, has a high potential for degradation
into reducing sugars, and subsequent conversion into bioethanol. This process requires a …
into reducing sugars, and subsequent conversion into bioethanol. This process requires a …
[HTML][HTML] Glycosidase mechanisms: Sugar conformations and reactivity in endo-and exo-acting enzymes
The enzymatic breakdown of carbohydrates plays a critical role in several biological events
and enables the development of sustainable processes to obtain bioproducts and biofuels …
and enables the development of sustainable processes to obtain bioproducts and biofuels …