[HTML][HTML] Bacteria-driven phthalic acid ester biodegradation: current status and emerging opportunities

R Hu, H Zhao, X Xu, Z Wang, K Yu, L Shu, Q Yan… - Environment …, 2021 - Elsevier
The extensive use of phthalic acid esters (PAEs) has led to their widespread distribution
across various environments. As PAEs pose significant threats to human health, it is urgent …

Co-culturing microbial consortia: approaches for applications in biomanufacturing and bioprocessing

RV Kapoore, G Padmaperuma, S Maneein… - Critical Reviews in …, 2022 - Taylor & Francis
The application of microbial co-cultures is now recognized in the fields of biotechnology,
ecology, and medicine. Understanding the biological interactions that govern the …

[HTML][HTML] Toward merging bottom–up and top–down model-based designing of synthetic microbial communities

D San León, J Nogales - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•Analysis and designing of microbiomes have become a new paradigm in
microbiology.•Understanding and rational engineering of microbiomes require model-based …

[HTML][HTML] Computational modeling of metabolism in microbial communities on a genome-scale

AV Colarusso, I Goodchild-Michelman, M Rayle… - Current Opinion in …, 2021 - Elsevier
Computational modeling of microbial communities using GEnome-scale Models (GEMs) of
metabolism is a new frontier in systems biology. Here, we discuss recent developments in …

[HTML][HTML] Metabolomics and modelling approaches for systems metabolic engineering

JK Khanijou, H Kulyk, C Bergès, LW Khoo, P Ng… - Metabolic Engineering …, 2022 - Elsevier
Metabolic engineering involves the manipulation of microbes to produce desirable
compounds through genetic engineering or synthetic biology approaches. Metabolomics …

[HTML][HTML] Modelling microbial communities: Harnessing consortia for biotechnological applications

M Ibrahim, L Raajaraam, K Raman - Computational and Structural …, 2021 - Elsevier
Microbes propagate and thrive in complex communities, and there are many benefits to
studying and engineering microbial communities instead of single strains. Microbial …

[HTML][HTML] Advances in flux balance analysis by integrating machine learning and mechanism-based models

A Sahu, MA Blätke, JJ Szymański, N Töpfer - Computational and structural …, 2021 - Elsevier
The availability of multi-omics data sets and genome-scale metabolic models for various
organisms provide a platform for modeling and analyzing genotype-to-phenotype …

[HTML][HTML] Soil metabolomics-current challenges and future perspectives

RW Brown, MK Reay, F Centler, DR Chadwick… - Soil Biology and …, 2024 - Elsevier
Soil is an extremely complex and dynamic matrix, in part, due to the wide diversity of
organisms living within it. Soil organic matter (SOM) is the fundamental substrate on which …

Metabolic models of human gut microbiota: Advances and challenges

DR Garza, D Gonze, H Zafeiropoulos, B Liu, K Faust - Cell systems, 2023 - cell.com
The human gut is a complex ecosystem consisting of hundreds of microbial species
interacting with each other and with the human host. Mathematical models of the gut …

Metagenome-scale community metabolic modelling for understanding the role of gut microbiota in human health

S Beura, P Kundu, AK Das, A Ghosh - Computers in biology and medicine, 2022 - Elsevier
Metabolic activities of the microbial population are important to maintain the balance of
almost all the ecosystems on earth. In the human gut environment, these microbial …