Sex differences and stress across the lifespan

TL Bale, CN Epperson - Nature neuroscience, 2015 - nature.com
Sex differences in stress responses can be found at all stages of life and are related to both
the organizational and activational effects of gonadal hormones and to genes on the sex …

Sex differences and the neurobiology of affective disorders

DR Rubinow, PJ Schmidt - Neuropsychopharmacology, 2019 - nature.com
Observations of the disproportionate incidence of depression in women compared with men
have long preceded the recent explosion of interest in sex differences. Nonetheless, the …

[HTML][HTML] Progesterone–friend or foe?

I Sundström-Poromaa, E Comasco, R Sumner… - Frontiers in …, 2020 - Elsevier
Estradiol is the “prototypic” sex hormone of women. Yet, women have another sex hormone,
which is often disregarded: Progesterone. The goal of this article is to provide a …

Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder

HM Abdolmaleky, S Yaqubi, P Papageorgis… - Schizophrenia …, 2011 - Elsevier
Introduction HTR2A gene has been the subject of numerous studies in psychiatric genetics
because LSD, which resembles serotonin causes psychosis and atypical antipsychotic …

[HTML][HTML] Neural regeneration therapies for Alzheimer's and Parkinson's disease-related disorders

AP Reddy, J Ravichandran, N Carkaci-Salli - Biochimica et Biophysica Acta …, 2020 - Elsevier
Neurodegenerative diseases are devastating mental illnesses without a cure. Alzheimer's
disease (AD) characterized by memory loss, multiple cognitive impairments, and changes in …

Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice

L Gutknecht, S Popp, J Waider, FMJ Sommerlandt… - …, 2015 - Springer
Rationale While brain serotonin (5-HT) function is implicated in gene-by-environment
interaction (GxE) impacting the vulnerability-resilience continuum in neuropsychiatric …

The menstrual cycle influences emotion but has limited effect on cognitive function

I Sundström-Poromaa - Vitamins and hormones, 2018 - Elsevier
From a psychological perspective, the menstrual cycle has been a research topic for more
than 50 years. The most recent menstrual cycle research has been driven by an increased …

Serotonin-estrogen interactions: What can we learn from pregnancy?

AAH Thibeault, JT Sanderson, C Vaillancourt - Biochimie, 2019 - Elsevier
We have reviewed the scientific literature related to four diseases in which to serotonin (5-
HT) is involved in the etiology, herein named 5-HT-linked diseases, and whose prevalence …

Interactive effects of estrogen and serotonin on brain activation during working memory and affective processing in menopausal women

CN Epperson, Z Amin, K Ruparel, R Gur… - …, 2012 - Elsevier
While cognitive changes and mood instability are frequent symptoms reported by
menopausal women, the degree to which the decline in estrogen production is responsible …

Steroids and neuroprotection: new advances

LM Garcia-Segura, J Balthazart - Frontiers in Neuroendocrinology, 2009 - Elsevier
Gonadal hormones exert neuroprotective actions. In addition, it has become evident that the
local synthesis of these molecules in the central nervous system may prevent or reduce …