Improving translation of animal models of addiction and relapse by reverse translation
Critical features of human addiction are increasingly being incorporated into complementary
animal models, including escalation of drug intake, punished drug seeking and taking …
animal models, including escalation of drug intake, punished drug seeking and taking …
[HTML][HTML] Sex differences in the neurobiology of alcohol use disorder
A Flores-Bonilla, HN Richardson - Alcohol research: current …, 2020 - ncbi.nlm.nih.gov
Sex differences may play a critical role in modulating how chronic or heavy alcohol use
impacts the brain to cause the development of alcohol use disorder (AUD). AUD is a …
impacts the brain to cause the development of alcohol use disorder (AUD). AUD is a …
[HTML][HTML] Preclinical and clinical evidence for suppression of alcohol intake by apremilast
KB Grigsby, RA Mangieri, AJ Roberts… - The Journal of …, 2023 - Am Soc Clin Investig
JCI - Preclinical and clinical evidence for suppression of alcohol intake by apremilast Go to
JCI Insight About Editors Consulting Editors For authors Publication ethics Alerts Advertising …
JCI Insight About Editors Consulting Editors For authors Publication ethics Alerts Advertising …
[HTML][HTML] Understanding addiction using animal models
Drug addiction is a neuropsychiatric disorder with grave personal consequences that has an
extraordinary global economic impact. Despite decades of research, the options available to …
extraordinary global economic impact. Despite decades of research, the options available to …
A cortical-brainstem circuit predicts and governs compulsive alcohol drinking
What individual differences in neural activity predict the future escalation of alcohol drinking
from casual to compulsive? The neurobiological mechanisms that gate the transition from …
from casual to compulsive? The neurobiological mechanisms that gate the transition from …
[HTML][HTML] Dopamine circuit mechanisms of addiction-like behaviors
CL Poisson, L Engel, BT Saunders - Frontiers in Neural Circuits, 2021 - frontiersin.org
Addiction is a complex disease that impacts millions of people around the world. Clinically,
addiction is formalized as substance use disorder (SUD), with three primary symptom …
addiction is formalized as substance use disorder (SUD), with three primary symptom …
[HTML][HTML] Recent perspectives on sex differences in compulsion-like and binge alcohol drinking
AK Radke, EA Sneddon, RM Frasier… - International Journal of …, 2021 - mdpi.com
Alcohol use disorder remains a substantial social, health, and economic problem and
problem drinking levels in women have been increasing in recent years. Understanding …
problem drinking levels in women have been increasing in recent years. Understanding …
Sex differences in binge‐like and aversion‐resistant alcohol drinking in C57 BL/6J mice
EA Sneddon, RD White… - Alcoholism: clinical and …, 2019 - Wiley Online Library
Background Alcohol use disorder is characterized by compulsive alcohol intake, or drinking
despite negative consequences. Previous studies have shown that female rodents have a …
despite negative consequences. Previous studies have shown that female rodents have a …
[HTML][HTML] Defining compulsive behavior
Compulsive tendencies are a central feature of problematic human behavior and thereby
are of great interest to the scientific and clinical community. However, no consensus exists …
are of great interest to the scientific and clinical community. However, no consensus exists …
[HTML][HTML] Pathological overeating: emerging evidence for a compulsivity construct
Compulsive eating behavior is a transdiagnostic construct that is characteristic of medical
and psychiatric conditions such as forms of obesity and eating disorders. Although feeding …
and psychiatric conditions such as forms of obesity and eating disorders. Although feeding …