Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

Reactive oxygen species (ROS)-dependent production of ROS underlies sustained
oxidative stress, which has been implicated in the pathogenesis of cardiovascular diseases …

Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterized by an
abnormal reepithelialisation, an excessive tissue remodelling and a progressive fibrosis …

Significance: Oxidative stress, an excess of reactive oxygen species (ROS) production
versus consumption, may be involved in the pathogenesis of different diseases. The only …

NADPH oxidases are a family of enzymes that generate reactive oxygen species (ROS). The
NOX1 (NADPH oxidase 1) and NOX2 oxidases are the major sources of ROS in the artery …

For a long time, superoxide generation by an NADPH oxidase was considered as an oddity
only found in professional phagocytes. Over the last years, six homologs of the cytochrome …

Significance: Reactive oxygen species (ROS) play a critical role in vascular disease. While
there are many possible sources of ROS, nicotinamide adenine dinucleotide phosphate …

The signaling pathways involved in the long-term metabolic effects of angiotensin II (Ang II)
in vascular smooth muscle cells are incompletely understood but include the generation of …

Understanding the molecular mechanisms that promote successful tissue regeneration is
critical for continued advancements in regenerative medicine. Vertebrate amphibian …