The roles of diacylglycerol kinase α in cancer cell proliferation and apoptosis

F Sakane, F Hoshino, M Ebina, H Sakai, D Takahashi - Cancers, 2021 - mdpi.com
Simple Summary Diacylglycerol (DG) kinase (DGK) phosphorylates DG to generate
phosphatidic acid (PA). DGKα is highly expressed in several refractory cancer cells …

[HTML][HTML] Health promoting activities and corresponding mechanism of (–)-epicatechin-3-gallate

Z Li, C Feng, H Dong, W Jin, W Zhang, J Zhan… - Food Science and …, 2022 - Elsevier
Epicatechin-3-gallate (ECG), a bioactive polyphenolic compound, has contributed a lot to
the health benefits of green tea. Great attention has been focused on (–)-epigallocatechin-3 …

A novel functional full-fat hard cheese containing liposomal nanoencapsulated green tea catechins: Manufacture and recovery following simulated digestion

A Rashidinejad, EJ Birch, DW Everett - Food & function, 2016 - pubs.rsc.org
(+)-Catechin or green tea extract were encapsulated in soy lecithin nanoliposomes and
incorporated into a full-fat cheese, then ripened at 8° C for 90 days. Cheese samples were …

Vitamin E functions by association with a novel binding site on the 67 kDa laminin receptor activating diacylglycerol kinase

D Hayashi, VD Mouchlis, S Okamoto, T Namba… - The Journal of nutritional …, 2022 - Elsevier
It is generally recognized that the main function of α-tocopherol (αToc), which is the most
active form of vitamin E, is its antioxidant effect, while non-antioxidant effects have also been …

The mechanisms of ameliorating effect of a green tea polyphenol on diabetic nephropathy based on diacylglycerol kinase α

D Hayashi, L Wang, S Ueda, M Yamanoue… - Scientific Reports, 2020 - nature.com
Significant efforts have been made to ameliorate diabetic nephropathy (DN) by inhibiting
protein kinase C. However, these efforts have not been successful in human trials …

The role of diacylglycerol kinase in the amelioration of diabetic nephropathy

D Hayashi, Y Shirai - Molecules, 2022 - mdpi.com
The drastic increase in the number of patients with diabetes and its complications is a global
issue. Diabetic nephropathy, the leading cause of chronic kidney disease, significantly …

[HTML][HTML] Cyanidin-3-glucoside from black rice prevents renal dysfunction and renal fibrosis in streptozotocin-diabetic rats

SS Qi, J He, LP Yuan, J Le Wu, YX Zu… - Journal of Functional …, 2020 - Elsevier
Hyperglycemia, increased inflammation, and mitochondrial dysfunction in diabetes may
eventually cause kidney damage. Black rice cyanidin-3-glucoside has anti-hyperglycemic …

Diacylglycerol kinase alpha is involved in the vitamin E-induced amelioration of diabetic nephropathy in mice

D Hayashi, K Yagi, C Song, S Ueda, M Yamanoue… - Scientific reports, 2017 - nature.com
Diabetic nephropathy (DN) is one of vascular complications of diabetes and is caused by
abnormal protein kinase C activation as a result of increased diacylglycerol (DG) production …

[HTML][HTML] Green tea infusion prevents diabetic nephropathy aggravation in recent-onset type 1 diabetes regardless of glycemic control

LCM Ladeira, EC Dos Santos, TA Santos… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Green tea, traditionally used as antidiabetic medicine,
positively affects the diabetic nephropathy. It was assumed that these beneficial effects were …

Amelioration of diabetic nephropathy by oral administration of d-α-tocopherol and its mechanisms

D Hayashi, S Ueda, M Yamanoue… - Bioscience …, 2018 - academic.oup.com
Diabetic nephropathy (DN) is a diabetic vascular complication, and abnormal protein kinase
C (PKC) activation from increased diacylglycerol (DG) production in diabetic hyperglycemia …