The lack of efficient therapeutic options for many severe disorders including cancer spurs
demand for improved drug delivery technologies. Nanoscale drug delivery systems based …

Nanoparticles enable the delivery of a great variety of drugs including anticancer drugs,
analgesics, anti-Alzheimer's drugs, cardiovascular drugs, protease inhibitors, and several …

Targeted delivery of therapeutic nanoparticles in a disease-specific manner represents a
potentially powerful technology especially when treating infiltrative brain tumors such as …

Paclitaxel is one of the most effective chemotherapeutic drugs ever developed and is active
against a broad range of cancers, such as lung, ovarian, and breast cancers. Due to its low …

Nanoengineered drug delivery systems (nDDS) have been successfully used as clinical
tools for not only modulation of pharmacological drug release profile but also specific …

Dual-targeting nanoparticle drug delivery system was developed by conjugating Angiopep
with PEG–PCL nanoparticles (ANG-NP) through bifunctional PEG to overcome the …

Therapeutic effect of glioma is often limited due to low permeability of delivery systems
across the Blood-Brain Barrier (BBB) and poor penetration into the tumor tissue. In order to …

Abstract Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past
few years. It is widely explored in drug delivery, where the development of nanomedicines …

Based on the facilitative glucose transporter (GLUT) over-expression on both blood–brain
barrier (BBB) and glioma cells, 2-deoxy-d-glucose modified poly (ethylene glycol)-co-poly …

Nanotheranostics is a relatively new, fast-growing field that combines the advantages of
treatment and diagnosis via a single nanoscale carrier. The ability to bundle both …