Compared to bare-metal stents (BMSs), drug-eluting stents (DESs) have been regarded as a
revolutionary change in coronary artery diseases (CADs). Releasing pharmaceutical agents …

Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …

Stroke remains the leading cause of long-term disability with limited options available to aid
in recovery. Significant effort has been made to try and minimize neuronal damage following …

Glycosaminoglycans (GAGs) in marine animals are different to those of terrestrial organisms,
mainly in terms of molecular weight and sulfation. The therapeutic properties of GAGs are …

Background The native extracellular matrix (ECM) consists of a highly complex, tissue-
specific network of proteins and polysaccharides, which help regulate many cellular …

EXECUTIVE SUMMARY The University of Vermont College of Medicine and the Vermont
Lung Center, with support of the National Heart, Lung, and Blood Institute (NHLBI), the …

Glycosaminoglycans (GAGs) play a crucial role in tissue homeostasis by regulating the
activity and diffusion of bioactive molecules. Incorporating GAGs into biomaterials has …

Currently available cardiovascular implants, such as heart valves and stents, exhibit
suboptimal biocompatibility because of the incomplete endothelialization and sequential …

In the history of biomedicine and biomedical devices, heart valve manufacturing techniques
have undergone a spectacular evolution. However, important limitations in the development …

Mesenchymal stem cells (MSCs) are currently under investigation as tools to preserve
cardiac structure and function following acute myocardial infarction (AMI). However …