Excessive alcohol intake is a direct cause of alcoholic liver disease (ALD). ALD usually
manifests as fatty liver in the initial stage and then develops into alcoholic hepatitis (ASH) …

Liver diseases are clinically common and present a substantial public health issue. Many of
the currently available drugs for the treatment of liver diseases suffer from limitations that …

Cryptotanshinone (CT), a diterpene that is isolated from Salvia miltiorrhiza Bunge, exhibits
anti-cancer, anti-oxidative, anti-fibrosis, and anti-inflammatory properties. Here, we …

Salvia miltiorrhiza is known for tanshinones and salvianolic acids, which have been shown
to have a protective effect against ROS, especially for cardiovascular diseases and other …

Liver diseases cause serious public health problems because of their high global
prevalence and poor long-term clinical outcomes. With its mild and broad therapeutic …

Although tanshinone IIA (Tan IIA) from Salviae miltiorrhizae was known to induce apoptosis
in various cancers, its underlying mechanism of autophagic cell death was not reported yet …

Because of its high prevalence and poor long-term clinical treatment effect, liver disease is
regarded as a major public health problem around the world. Among them, viral hepatitis …

Tanshinone IIA (TAN) is one of the major functional compounds of Salvia miltiorrhiza Bunge
and possesses the ability to suppress the growth of multiple cancer cell types via its …

Many cultivated and wild plants are used for the management of various diseases,
specifically renal and hepatic diseases and those of the immune and cardiovascular …

Following chronic liver injury, hepatocytes undergo apoptosis leading to activation of hepatic
stellate cells (HSC). Consequently, activated HSC proliferate and produce excessive …