Relevance of immune cell and tumor microenvironment imaging in the new era of immunotherapy
F Galli, JV Aguilera, B Palermo, SN Markovic… - Journal of experimental …, 2020 - Springer
Tumor-infiltrating immune cells play a key role against cancer. However, malignant cells are
able to evade the immune response and establish a very complex balance in which different …
able to evade the immune response and establish a very complex balance in which different …
[HTML][HTML] Novel PET imaging of inflammatory targets and cells for the diagnosis and monitoring of giant cell arteritis and polymyalgia rheumatica
Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two interrelated
inflammatory diseases affecting patients above 50 years of age. Patients with GCA suffer …
inflammatory diseases affecting patients above 50 years of age. Patients with GCA suffer …
Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers
The correspondence of cell state changes in diseased organs to peripheral protein
signatures is currently unknown. Here, we generated and integrated single‐cell …
signatures is currently unknown. Here, we generated and integrated single‐cell …
Targeting monocytes/macrophages in fibrosis and cancer diseases: Therapeutic approaches
E Conte - Pharmacology & Therapeutics, 2022 - Elsevier
Over almost 140 years since their identification, the knowledge about macrophages has
unbelievably evolved. The'big eaters' from being thought of as simple phagocytic cells have …
unbelievably evolved. The'big eaters' from being thought of as simple phagocytic cells have …
Imaging inflammation with positron emission tomography
J Iking, M Staniszewska, L Kessler, JM Klose… - Biomedicines, 2021 - mdpi.com
The impact of inflammation on the outcome of many medical conditions such as
cardiovascular diseases, neurological disorders, infections, cancer, and autoimmune …
cardiovascular diseases, neurological disorders, infections, cancer, and autoimmune …
Single-cell RNA sequencing reveals unique monocyte-derived interstitial macrophage subsets during lipopolysaccharide-induced acute lung inflammation
PK Moore, KC Anderson… - … of Physiology-Lung …, 2023 - journals.physiology.org
Interstitial macrophages (IMs) reside in the lung tissue surrounding key structures including
airways, vessels, and alveoli. Recent work has described IM heterogeneity during …
airways, vessels, and alveoli. Recent work has described IM heterogeneity during …
Folate receptor beta for macrophage imaging in rheumatoid arthritis
MM Steinz, A Ezdoglian, F Khodadust… - Frontiers in …, 2022 - frontiersin.org
Non-invasive imaging modalities constitute an increasingly important tool in diagnostic and
therapy response monitoring of patients with autoimmune diseases, including rheumatoid …
therapy response monitoring of patients with autoimmune diseases, including rheumatoid …
Functionally heterogenous macrophage subsets in the pathogenesis of giant cell arteritis: novel targets for disease monitoring and treatment
I Esen, WF Jiemy, Y van Sleen… - Journal of Clinical …, 2021 - mdpi.com
Giant cell arteritis (GCA) is a granulomatous large-vessel vasculitis that affects adults above
50 years of age. In GCA, circulating monocytes are recruited to the inflamed arteries. With …
50 years of age. In GCA, circulating monocytes are recruited to the inflamed arteries. With …
Monitoring of current cancer therapy by positron emission tomography and possible role of radiomics assessment
N Oriuchi, H Endoh, K Kaira - International Journal of Molecular Sciences, 2022 - mdpi.com
Evaluation of cancer therapy with imaging is crucial as a surrogate marker of effectiveness
and survival. The unique response patterns to therapy with immune-checkpoint inhibitors …
and survival. The unique response patterns to therapy with immune-checkpoint inhibitors …
[HTML][HTML] Novel tracers for molecular imaging of interstitial lung disease: A state of the art review
B Broens, JW Duitman, GJC Zwezerijnen… - Autoimmunity …, 2022 - Elsevier
Interstitial lung disease is an overarching term for a wide range of disorders characterized by
inflammation and/or fibrosis in the lungs. Most prevalent forms, among others, include …
inflammation and/or fibrosis in the lungs. Most prevalent forms, among others, include …