Challenges and opportunities for digital twins in precision medicine: a complex systems perspective
M De Domenico, L Allegri, G Caldarelli… - arXiv preprint arXiv …, 2024 - arxiv.org
The adoption of digital twins (DTs) in precision medicine is increasingly viable, propelled by
extensive data collection and advancements in artificial intelligence (AI), alongside …
extensive data collection and advancements in artificial intelligence (AI), alongside …
myAURA: Personalized health library for epilepsy management via knowledge graph sparsification and visualization
Objective: We report the development of the patient-centered myAURA application and suite
of methods designed to aid epilepsy patients, caregivers, and researchers in making …
of methods designed to aid epilepsy patients, caregivers, and researchers in making …
Pervasive relaxed selection on spermatogenesis genes coincident with the evolution of polygyny in gorillas
J Bowman, N Silva, E Schüueftan, JM Almeida… - bioRxiv, 2023 - biorxiv.org
Gorillas have a polygynous social system in which the highest-ranking male has almost
exclusive access to females and sires most of the offspring in the troop. Such behavior …
exclusive access to females and sires most of the offspring in the troop. Such behavior …
Regulatory changes associated with the head to trunk developmental transition
P Duarte, R Brattig Correia, A Nóvoa, M Mallo - BMC biology, 2023 - Springer
Background Development of vertebrate embryos is characterized by early formation of the
anterior tissues followed by the sequential extension of the axis at their posterior end to build …
anterior tissues followed by the sequential extension of the axis at their posterior end to build …
[HTML][HTML] Dynamical modularity in automata models of biochemical networks
T Parmer, LM Rocha - ArXiv, 2023 - ncbi.nlm.nih.gov
Given the large size and complexity of most biochemical regulation and signaling networks,
there is a non-trivial relationship between the micro-level logic of component interactions …
there is a non-trivial relationship between the micro-level logic of component interactions …
The ultrametric backbone is the union of all minimum spanning forests
Minimum spanning trees and forests are powerful sparsification techniques that remove
cycles from weighted graphs to minimize total edge weight while preserving node …
cycles from weighted graphs to minimize total edge weight while preserving node …
Shifting Gears: Insights into the Head to Trunk Transition Exploring the Regulatory Changes Underlying the Head to Trunk Developmental Transition
P Duarte - 2023 - search.proquest.com
Although vertebrates display a wide diversity of body shapes and sizes their basic body plan
is consistently organized into head, neck, trunk and tail structures. During development, the …
is consistently organized into head, neck, trunk and tail structures. During development, the …
[PDF][PDF] Shifting gears: Insights into the head to trunk transition
P Duarte - run.unl.pt
To Moisés for the opportunity of joining the lab and working on this project, thank you for
your guidance and support. To all the past and present members of the lab I had the …
your guidance and support. To all the past and present members of the lab I had the …