Biomimetic peptide self-assembly for functional materials
Natural biomolecular systems have evolved to form a rich variety of supramolecular
materials and machinery fundamental to cellular function. The assembly of these structures …
materials and machinery fundamental to cellular function. The assembly of these structures …
Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology
Self-assembled peptide and protein amyloid nanostructures have traditionally been
considered only as pathological aggregates implicated in human neurodegenerative …
considered only as pathological aggregates implicated in human neurodegenerative …
Histidine as a key modulator of molecular self-assembly: Peptide-based supramolecular materials inspired by biological systems
Histidine, a versatile proteinogenic amino acid, plays a broad range of roles in all living
organisms and behaves as a key mediator of the interactions of biomolecules with inorganic …
organisms and behaves as a key mediator of the interactions of biomolecules with inorganic …
pH-Sensitive nanogates based on poly (l-histidine) for controlled drug release from mesoporous silica nanoparticles
The design and synthesis of novel poly (L-histidine)-grafted mesoporous silica nanoparticles
(MSNs) by a surface-initiated ring-opening polymerization process (ROP) is reported. Using …
(MSNs) by a surface-initiated ring-opening polymerization process (ROP) is reported. Using …
Peptide-templated noble metal catalysts: syntheses and applications
Noble metal catalysts have been widely used in many applications because of their high
activity and selectivity. However, a controllable preparation of noble metal catalysts still …
activity and selectivity. However, a controllable preparation of noble metal catalysts still …
Self-healing pH-and enzyme stimuli-responsive hydrogels for targeted delivery of gemcitabine to treat pancreatic cancer
P Bilalis, D Skoulas, A Karatzas, J Marakis… - …, 2018 - ACS Publications
A novel, multifunctional hydrogel that exhibits a unique set of properties for the effective
treatment of pancreatic cancer (PC) is presented. The material is composed of a pentablock …
treatment of pancreatic cancer (PC) is presented. The material is composed of a pentablock …
Cofibrillization of pathogenic and functional amyloid proteins with gold nanoparticles against amyloidogenesis
Biomimetic nanocomposites and scaffolds hold the key to a wide range of biomedical
applications. Here we show, for the first time, a facile scheme of cofibrillizing pathogenic and …
applications. Here we show, for the first time, a facile scheme of cofibrillizing pathogenic and …
Geometrical assembly of ultrastable protein templates for nanomaterials
DJ Glover, L Giger, SS Kim, RR Naik… - Nature communications, 2016 - nature.com
The fabrication of nanoscale devices requires architectural templates on which to position
functional molecules in complex arrangements. Protein scaffolds are particularly promising …
functional molecules in complex arrangements. Protein scaffolds are particularly promising …
Hierarchical self-assembly of histidine-functionalized peptide amphiphiles into supramolecular chiral nanostructures
Controlling the hierarchical organization of self-assembling peptide amphiphiles into
supramolecular nanostructures opens up the possibility of developing biocompatible …
supramolecular nanostructures opens up the possibility of developing biocompatible …
Mimicry of silk utilizing synthetic polypeptides
For thousands of years,'silk'and silk-based materials have played an important role for
mankind. Today, silk-based materials increasingly find use in novel application areas such …
mankind. Today, silk-based materials increasingly find use in novel application areas such …