[HTML][HTML] Diagnostics using non-invasive technologies in dermatological oncology

S Soglia, J Pérez-Anker, N Lobos Guede, P Giavedoni… - Cancers, 2022 - mdpi.com
Simple Summary Skin tumors are appearing with increasing frequency worldwide. To face
this health problem, new technologies and devices have been developed in recent years …

Multiphoton microscopy in surgical oncology-a systematic review and guide for clinical translatability

TT König, J Goedeke, OJ Muensterer - Surgical Oncology, 2019 - Elsevier
Background Multiphoton microscopy (MPM) facilitates three-dimensional, high-resolution
functional imaging of unlabeled tissues in vivo and ex vivo. This systematic review discusses …

Support vector machine classification of nonmelanoma skin lesions based on fluorescence lifetime imaging microscopy

B Chen, Y Lu, W Pan, J Xiong, Z Yang, W Yan… - Analytical …, 2019 - ACS Publications
Early diagnosis of malignant skin lesions is critical for prompt treatment and a clinical
prognosis of skin cancers. However, it is difficult to precisely evaluate the development stage …

Multiphoton microscopy of the dermoepidermal junction and automated identification of dysplastic tissues with deep learning

MJ Huttunen, R Hristu, A Dumitru, I Floroiu… - Biomedical optics …, 2019 - opg.optica.org
Histopathological image analysis performed by a trained expert is currently regarded as the
gold-standard for the diagnostics of many pathologies, including cancers. However, such …

Phasor–FLIM as a Screening tool for the differential diagnosis of actinic keratosis, Bowen's disease, and basal cell carcinoma

T Luo, Y Lu, S Liu, D Lin, J Qu - Analytical chemistry, 2017 - ACS Publications
The aim of this study was to distinguish basal cell carcinoma (BCC) from actinic keratosis
(AK) and Bowen's disease (BD) by fluorescence lifetimes of hematoxylin and eosin (H&E) …

Imaging microphysiological systems: A review

S Peel, M Jackman - American Journal of Physiology-Cell …, 2021 - journals.physiology.org
Microphysiological systems (MPS), often referred to as “organ-on-chips,” are microfluidic-
based in vitro models that aim to recapitulate the dynamic chemical and mechanical …

Recent advances in multiphoton microscopy combined with nanomaterials in the field of disease evolution and clinical applications to liver cancer

H Lin, T Fan, J Sui, G Wang, J Chen, S Zhuo, H Zhang - Nanoscale, 2019 - pubs.rsc.org
Multiphoton microscopy (MPM) is expected to become a powerful clinical tool, with its
unique advantages of being label-free, high resolution, deep imaging depth, low light …

Review of optical methods for noninvasive imaging of skin fibroblasts—From in vitro to ex vivo and in vivo visualization

VV Nikolaev, YV Kistenev, M Kröger… - Journal of …, 2024 - Wiley Online Library
Fibroblasts are among the most common cell types in the stroma responsible for creating
and maintaining the structural organization of the extracellular matrix in the dermis, skin …

[HTML][HTML] Pharmacological Agents Targeting Drug-Tolerant Persister Cells in Cancer

YC Chen, K Gowda, S Amin, TD Schell… - Pharmacological …, 2024 - Elsevier
Current cancer therapy can be effective, but the development of drug resistant disease is the
usual outcome. These drugs can eliminate most of the tumor burden but often fail to …

[PDF][PDF] 多光子显微技术在乳腺肿瘤微环境预后预测研究中的应用进展

徐顺武, 何佳佳, 席刚琴, 李连煌, 韩侠辉… - Laser & …, 2022 - researching.cn
摘要长期以来, 乳腺癌的发病率占据全球女性恶性肿瘤发病率的首位. 国际癌症研究机构最新
发布的2020 年全球癌症负担数据显示, 乳腺癌在全球发病数超过了肺癌, 成为全球第一大癌 …