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ABSTRACT Objectives The World Health Organization estimated that a quarter of the global
population is infected by Mycobacterium tuberculosis (Mtb). A better control of tuberculosis …

Comprehensive guidelines for treatment of latent tuberculosis infection (LTBI) among
persons living in the United States were last published in 2000 (American Thoracic Society …

Executive summary Tuberculosis (TB) strains with drug resistance (DR-TB) are more difficult
to treat than drug-susceptible ones, and threaten global progress towards the targets set by …

1.1 Background Latent tuberculosis infection (LTBI) is defined as a state of persistent
immune response to stimulation by Mycobacterium tuberculosis antigens with no evidence …

Background A 9-month regimen of isoniazid can prevent active tuberculosis in persons with
latent tuberculosis infection. However, the regimen has been associated with poor …

The WHO consolidated guidelines on tuberculosis: tuberculosis preventive treatment
provides a comprehensive set of recommendations for programmatic management of …

Background: Treatment of latent tuberculosis infection (LTBI) is an important component of
tuberculosis (TB) control, and this study updates a previous network meta-analysis of the …

BACKGROUND: Tuberculosis (TB) preventive therapy (TPT) decreases the risk of
developing TB disease and its associated morbidity and mortality. The aim of these clinical …

Background The treatment of latent infection with Mycobacterium tuberculosis is important in
children because of their vulnerability to life-threatening forms of tuberculosis disease. The …