Microbiome: role in inflammatory skin diseases

XE Zhang, P Zheng, SZ Ye, X Ma, E Liu… - Journal of …, 2024 - Taylor & Francis
As the body's largest organ, the skin harbors a highly diverse microbiota, playing a crucial
role in resisting foreign pathogens, nurturing the immune system, and metabolizing natural …

[HTML][HTML] Topoisomeric Membrane-Active Peptides: A Review of the Last Two Decades

A Carrera-Aubesart, M Gallo, S Defaus, T Todorovski… - Pharmaceutics, 2023 - mdpi.com
In recent decades, bioactive peptides have been gaining recognition in various biomedical
areas, such as intracellular drug delivery (cell-penetrating peptides, CPPs) or anti-infective …

Liposomes encapsulating novel antimicrobial peptide Omiganan: Characterization and its pharmacodynamic evaluation in atopic dermatitis and psoriasis mice model

A Javia, A Misra, H Thakkar - International Journal of Pharmaceutics, 2022 - Elsevier
Omiganan is a novel 12 amino acid synthetic cationic peptide from the cathelicidin family.
Omiganan possesses antimicrobial action against a wide range of microbes, including gram …

[HTML][HTML] An infection-microenvironment-targeted and responsive peptide-drug nanosystem for sepsis emergency by suppressing infection and inflammation

W He, D Fu, Y Gai, X Liu, C Yang, Z Ye, X Chen… - Asian Journal of …, 2023 - Elsevier
Sepsis is a life-threatening emergency that causes millions of deaths every year due to
severe infection and inflammation. Nevertheless, current therapeutic regimens are …

[HTML][HTML] The Antimicrobial Activity of Omiganan Alone and In Combination against Candida Isolated from Vulvovaginal Candidiasis and Bloodstream Infections

D Żyrek, A Wajda, P Czechowicz, J Nowicka… - Antibiotics, 2021 - mdpi.com
Fungi from the Candida genus are widespread commensals and, at the same time, are the
leading cause of fungal infections worldwide. For instance, vulvovaginal candidiasis (VVC) …

[HTML][HTML] Antifungal activity of linear and disulfide-cyclized ultrashort cationic lipopeptides alone and in combination with fluconazole against vulvovaginal Candida spp.

P Czechowicz, D Neubauer, J Nowicka, W Kamysz… - Pharmaceutics, 2021 - mdpi.com
Vulvovaginal candidiasis (VVC) occurs in over 75% of women at least once during their
lifetime and is an infection that significantly affects their health. Candida strains resistant to …

[HTML][HTML] Anti-Microbial Activities of Mussel-Derived Recombinant Proteins against Gram-Negative Bacteria

DY Kim, YB Oh, JS Park, YH Min, MC Park - Antibiotics, 2024 - mdpi.com
Many anti-microbial peptides (AMPs) and pro-apoptotic peptides are considered as novel
anti-microbial agents, distinguished by their different characteristics. Nevertheless, AMPs …

Synthesized peptide analogs from Eumenes pomiformis (Hymenoptera: Eumenidae) venom reveals their antibiotic and pesticide activity potential

R de la Salud Bea, E Frawley, Q Shen, S Moyo… - Toxicon, 2023 - Elsevier
One natural antimicrobial peptide (EpVP2a, Eumenes pomiformis Venom Peptide 2a) found
in the venom of a potter wasp (Eumenes pomiformis) and six analogs were synthesized and …