International union of basic and clinical pharmacology CXIII: Nuclear receptor superfamily—Update 2023
The NR superfamily comprises 48 transcription factors in humans that control a plethora of
gene network programs involved in a wide range of physiologic processes. This review will …
gene network programs involved in a wide range of physiologic processes. This review will …
Flindissone, a Limonoid Isolated from Trichilia prieuriana, Is an LXR Agonist
In this study, the ability of six limonoids from Trichilia prieuriana (Meliaceae) to activate the
liver X receptor (LXR) was assessed. One of these limonoids, flindissone, was shown to …
liver X receptor (LXR) was assessed. One of these limonoids, flindissone, was shown to …
[HTML][HTML] Identification of oxysterol synthetic analogs as a novel class of late-stage inhibitors of herpes simplex virus 2 replication
Genital herpes, most frequently caused by herpes simplex virus 2 (HSV-2) infection, is one
of the most prevalent sexually transmitted infections. The current rationale for the treatment …
of the most prevalent sexually transmitted infections. The current rationale for the treatment …
[HTML][HTML] Cholenamide-based, antiviral fluorescent probes targeting oxysterol-binding protein
F Nigro, A Civra, D Porporato, M Costantino… - Bioorganic …, 2024 - Elsevier
Oxysterols (OSs) represent a large family of cholesterol-derived molecules, involved in
several physiological and pathological processes. Recently, we reported the remarkable …
several physiological and pathological processes. Recently, we reported the remarkable …