Metaheuristic Biclustering Algorithms: From State-of-the-Art to Future Opportunities

A José-García, J Jacques, V Sobanski… - ACM Computing …, 2023 - dl.acm.org
Biclustering is an unsupervised machine-learning technique that simultaneously clusters
rows and columns in a data matrix. Over the past two decades, the field of biclustering has …

Gene co-expression analysis for functional classification and gene–disease predictions

S Van Dam, U Vosa, A van der Graaf… - Briefings in …, 2018 - academic.oup.com
Gene co-expression networks can be used to associate genes of unknown function with
biological processes, to prioritize candidate disease genes or to discern transcriptional …

It is time to apply biclustering: a comprehensive review of biclustering applications in biological and biomedical data

J Xie, A Ma, A Fennell, Q Ma, J Zhao - Briefings in bioinformatics, 2019 - academic.oup.com
Biclustering is a powerful data mining technique that allows clustering of rows and columns,
simultaneously, in a matrix-format data set. It was first applied to gene expression data in …

miR-142-5p enhances cisplatin-induced apoptosis in ovarian cancer cells by targeting multiple anti-apoptotic genes

X Li, W Chen, Y Jin, R Xue, J Su, Z Mu, J Li… - Biochemical …, 2019 - Elsevier
Chemotherapy is the preferred treatment for advanced ovarian cancer, but the 5-year
survival rate remains low partly because of the development of drug resistance. Although it …

Molecular mechanisms underlying lymphovascular invasion in invasive breast cancer

MA Aleskandarany, SN Sonbul, A Mukherjee… - Pathobiology, 2015 - karger.com
Lymphovascular invasion (LVI), the presence of malignant cells within lymphovascular
channels, is a crucial step in the invasion-metastasis cascade. LVI, when identified …

(Differential) co-expression analysis of gene expression: a survey of best practices

HA Chowdhury, DK Bhattacharyya… - IEEE/ACM transactions …, 2019 - ieeexplore.ieee.org
Analysis of gene expression data is widely used in transcriptomic studies to understand
functions of molecules inside a cell and interactions among molecules. Differential co …

[HTML][HTML] MiR-29a promotes cell proliferation and EMT in breast cancer by targeting ten eleven translocation 1

Y Pei, Y Lei, X Liu - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2016 - Elsevier
Increasing evidence has shown that microRNAs played an important role in regulating
carcinogenesis. However, the role of miR-29a in breast cancer is still unclear. Herein, we …

Mapping theme trends and recognizing hot spots in postmenopausal osteoporosis research: a bibliometric analysis

S Zhou, Z Tao, Y Zhu, L Tao - PeerJ, 2019 - peerj.com
Background This study aimed to draw a series of scientific maps to quantitatively and
qualitatively evaluate hot spots and trends in postmenopausal osteoporosis research using …

A multiobjective Bayesian networks approach for joint prediction of tumor local control and radiation pneumonitis in nonsmall‐cell lung cancer (NSCLC) for response …

Y Luo, DL McShan, MM Matuszak, D Ray… - Medical …, 2018 - Wiley Online Library
Purpose Individualization of therapeutic outcomes in NSCLC radiotherapy is likely to be
compromised by the lack of proper balance of biophysical factors affecting both tumor local …

Development of a fully cross-validated Bayesian network approach for local control prediction in lung cancer

Y Luo, D McShan, D Ray, M Matuszak… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
The purpose of this paper is to demonstrate that a Bayesian network (BN) approach can
explore hierarchical biophysical relationships that influence tumor response and predict …