Applications of nanoparticles in biomedical imaging

X Han, K Xu, O Taratula, K Farsad - Nanoscale, 2019 - pubs.rsc.org
An urgent need for early detection and diagnosis of diseases continuously pushes the
advancements of imaging modalities and contrast agents. Current challenges remain for fast …

Gold nanostructures: synthesis, properties, and neurological applications

I Zare, MT Yaraki, G Speranza, AH Najafabadi… - Chemical society …, 2022 - pubs.rsc.org
Recent advances in technology are expected to increase our current understanding of
neuroscience. Nanotechnology and nanomaterials can alter and control neural functionality …

Golden exosomes selectively target brain pathologies in neurodegenerative and neurodevelopmental disorders

N Perets, O Betzer, R Shapira, S Brenstein, A Angel… - Nano …, 2019 - ACS Publications
Exosomes, nanovesicles that are secreted by different cell types, enable intercellular
communication at local or distant sites. Alhough they have been found to cross the blood …

In Vivo Neuroimaging of Exosomes Using Gold Nanoparticles

O Betzer, N Perets, A Angel, M Motiei, T Sadan… - ACS …, 2017 - ACS Publications
Exosomes are emerging as effective therapeutic tools for various pathologies. These
extracellular vesicles can bypass biological barriers, including the blood-brain barrier, and …

The effect of nanoparticle size on the ability to cross the blood–brain barrier: an in vivo study

O Betzer, M Shilo, R Opochinsky, E Barnoy… - …, 2017 - Taylor & Francis
Aim: Our goal was to develop an efficient nanoparticle-based system that can overcome the
restrictive mechanism of the blood–brain barrier (BBB) by targeting insulin receptors and …

Nanomedicine for Cancer Immunotherapy: Tracking Cancer-Specific T-Cells in Vivo with Gold Nanoparticles and CT Imaging

R Meir, K Shamalov, O Betzer, M Motiei… - ACS …, 2015 - ACS Publications
Application of immune cell-based therapy in routine clinical practice is challenging due to
the poorly understood mechanisms underlying success or failure of treatment. Development …

Recent advances in molecular imaging with gold nanoparticles

M Bouché, JC Hsu, YC Dong, J Kim, K Taing… - Bioconjugate …, 2019 - ACS Publications
Gold nanoparticles (AuNP) have been extensively developed as contrast agents, theranostic
platforms, and probes for molecular imaging. This popularity has yielded a large number of …

Nanoparticle contrast agents for X‐ray imaging applications

JC Hsu, LM Nieves, O Betzer, T Sadan… - Wiley …, 2020 - Wiley Online Library
X‐ray imaging is the most widely used diagnostic imaging method in modern medicine and
several advanced forms of this technology have recently emerged. Iodinated molecules and …

[HTML][HTML] In vivo small animal micro-CT using nanoparticle contrast agents

JR Ashton, JL West, CT Badea - Frontiers in pharmacology, 2015 - frontiersin.org
Computed tomography (CT) is one of the most valuable modalities for in vivo imaging
because it is fast, high-resolution, cost-effective, and non-invasive. Moreover, CT is heavily …

Non-genetic engineering of cells for drug delivery and cell-based therapy

Q Wang, H Cheng, H Peng, H Zhou, PY Li… - Advanced drug delivery …, 2015 - Elsevier
Cell-based therapy is a promising modality to address many unmet medical needs. In
addition to genetic engineering, material-based, biochemical, and physical science-based …