The evolution of the use of faecal microbiota transplantation and emerging therapeutic indications

JR Allegretti, BH Mullish, C Kelly, M Fischer - The Lancet, 2019 - thelancet.com
Developments in high-throughput microbial genomic sequencing and other systems biology
techniques have given novel insight into the potential contribution of the gut microbiota to …

International consensus conference on stool banking for faecal microbiota transplantation in clinical practice

G Cammarota, G Ianiro, CR Kelly, BH Mullish… - Gut, 2019 - gut.bmj.com
Although faecal microbiota transplantation (FMT) has a well-established role in the treatment
of recurrent Clostridioides difficile infection (CDI), its widespread dissemination is limited by …

Recipient factors in faecal microbiota transplantation: one stool does not fit all

C Danne, N Rolhion, H Sokol - Nature Reviews Gastroenterology & …, 2021 - nature.com
Faecal microbiota transplantation (FMT) is a promising therapy for chronic diseases
associated with gut microbiota alterations. FMT cures 90% of recurrent Clostridioides difficile …

Systematic review with meta‐analysis: efficacy of faecal microbiota transplantation for the treatment of irritable bowel syndrome

G Ianiro, LH Eusebi, CJ Black… - Alimentary …, 2019 - Wiley Online Library
Background Increasing evidence supports the role of the gut microbiota in the aetiology of
irritable bowel syndrome (IBS). Faecal microbiota transplantation (FMT) is a highly effective …

Fecal microbiota transplantation as new therapeutic avenue for human diseases

M Biazzo, G Deidda - Journal of Clinical Medicine, 2022 - mdpi.com
The human body is home to a variety of micro-organisms. Most of these microbial
communities reside in the gut and are referred to as gut microbiota. Over the last decades …

Beneficial effects of fecal microbiota transplantation in recurrent Clostridioides difficile infection

A Yadegar, S Pakpoor, FF Ibrahim, A Nabavi-Rad… - Cell host & …, 2023 - cell.com
Fecal microbiota transplantation (FMT) is highly effective in preventing recurrent
Clostridioides difficile infection (rCDI). However, the mechanisms underpinning its clinical …

Gut microbial β-glucuronidases regulate host luminal proteases and are depleted in irritable bowel syndrome

AL Edwinson, L Yang, S Peters, N Hanning… - Nature …, 2022 - nature.com
Intestinal proteases mediate digestion and immune signalling, while increased gut
proteolytic activity disrupts the intestinal barrier and generates visceral hypersensitivity …

Encyclopedia of fecal microbiota transplantation: a review of effectiveness in the treatment of 85 diseases

Y Wang, S Zhang, TJ Borody, F Zhang - Chinese Medical Journal, 2022 - journals.lww.com
Fecal microbiota transplantation (FMT) has been used as a core therapy for treating
dysbiosis-related diseases by remodeling gut microbiota. The methodology and technology …

Efficacy of fecal microbiota transplantation in irritable bowel syndrome: a meta-analysis of randomized controlled trials

J Wu, L Lv, C Wang - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
Background Randomized controlled trials (RCTs) have examined the efficacy of fecal
microbiota transplantation (FMT) in irritable bowel syndrome (IBS) with inconsistent results …

Randomised clinical trial: faecal microbiota transplantation versus autologous placebo administered via colonoscopy in irritable bowel syndrome

P Lahtinen, J Jalanka, A Hartikainen… - Alimentary …, 2020 - Wiley Online Library
Background Irritable bowel syndrome (IBS) has been associated with microbial dysbiosis.
Aim To investigate the efficacy of faecal microbiota transplantation (FMT) in the treatment of …