The contractile ring, which plays critical roles in cytokinesis in fungal and animal cells, has
fascinated biologists for decades. However, the basic question of how the non-muscle …

Cytokinesis by animals, fungi, and amoebas depends on actomyosin contractile rings, which
are stabilized by continuous turnover of actin filaments. Remarkably little is known about the …

Cytokinesis is executed by protein networks organized into functional modules. Individual
proteins within each module have been characterized to various degrees. However, the …

Cytokinesis, the separation of daughter cells at the end of mitosis, relies in animal cells on a
contractile actomyosin ring (CAR) composed of actin and class II myosins, whose activity is …

Successful separation of two daughter cells (ie, cytokinesis) is essential for life. Many
eukaryotic cells divide using a contractile apparatus called the cytokinetic ring (CR) that …

In fission yeast, the septation initiation network (SIN) ensures temporal coordination
between actomyosin ring (CAR) constriction with membrane ingression and septum …

Cytokinesis, which enables the physical separation of daughter cells once mitosis has been
completed, is executed in fungal and animal cells by a contractile actin-and myosin-based …

It is widely believed that cleavage-furrow formation during cytokinesis is driven by the
contraction of a ring containing F-actin and type-II myosin. However, even in cells that have …

Microscopy-based analysis of protein accumulation at a given subcellular location in real
time provides invaluable insights into the function of a protein in a specific process. Here, we …

Non-muscle myosin II activation by regulatory light chain (Rlc1 Sp) phosphorylation at Ser35
is crucial for cytokinesis during respiration in the fission yeast Schizosaccharomyces pombe …