The front and rear of collective cell migration

R Mayor, S Etienne-Manneville - Nature reviews Molecular cell biology, 2016 - nature.com
Collective cell migration has a key role during morphogenesis and during wound healing
and tissue renewal in the adult, and it is involved in cancer spreading. In addition to …

Genetics and genomics of congenital heart disease

S Zaidi, M Brueckner - Circulation research, 2017 - Am Heart Assoc
Congenital heart disease is the most common birth defect, and because of major advances
in medical and surgical management, there are now more adults living with congenital heart …

Dll4 and Notch signalling couples sprouting angiogenesis and artery formation

ME Pitulescu, I Schmidt, BD Giaimo, T Antoine… - Nature cell …, 2017 - nature.com
Endothelial sprouting and proliferation are tightly coordinated processes mediating the
formation of new blood vessels during physiological and pathological angiogenesis …

Collective cell migration in development

E Scarpa, R Mayor - Journal of cell Biology, 2016 - rupress.org
During embryonic development, tissues undergo major rearrangements that lead to germ
layer positioning, patterning, and organ morphogenesis. Often these morphogenetic …

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone

SK Ramasamy, AP Kusumbe, L Wang, RH Adams - Nature, 2014 - nature.com
Blood vessel growth in the skeletal system and osteogenesis seem to be coupled,
suggesting the existence of molecular crosstalk between endothelial and osteoblastic cells …

Retinal vasculature development in health and disease

S Selvam, T Kumar, M Fruttiger - Progress in retinal and eye research, 2018 - Elsevier
Abstract Development of the retinal vasculature is based on highly coordinated signalling
between different cell types of the retina, integrating internal metabolic requirements with …

Mechanisms of new blood-vessel formation and proliferative heterogeneity of endothelial cells

H Naito, T Iba, N Takakura - International immunology, 2020 - academic.oup.com
The vast blood-vessel network of the circulatory system is crucial for maintaining bodily
homeostasis, delivering essential molecules and blood cells, and removing waste products …

Lymphangiogenesis and lymphatic vessel remodelling in cancer

SA Stacker, SP Williams, T Karnezis, R Shayan… - Nature Reviews …, 2014 - nature.com
The generation of new lymphatic vessels through lymphangiogenesis and the remodelling
of existing lymphatics are thought to be important steps in cancer metastasis. The past …

[HTML][HTML] Broad targeting of angiogenesis for cancer prevention and therapy

Z Wang, C Dabrosin, X Yin, MM Fuster, A Arreola… - Seminars in cancer …, 2015 - Elsevier
Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

Blood flow controls bone vascular function and osteogenesis

SK Ramasamy, AP Kusumbe, M Schiller… - Nature …, 2016 - nature.com
While blood vessels play important roles in bone homeostasis and repair, fundamental
aspects of vascular function in the skeletal system remain poorly understood. Here we show …