Current diagnostic tests for tuberculosis based on tuberculin have poor specificity, and both
BCG vaccination and exposure to non-tuberculosis mycobacteria produce a response …

The early, preclinical stages of bovine TB can be detected in live animals by the use of tests
of cellular immunity (the skin, γ-interferon and lymphocyte transformation tests). Tests of …

Tuberculin tests in general use today rely on the response to intradermal injections of
tuberculin with assessment of the injection site for swelling at 72 hours post injection …

A tentative diagnosis of bovine tuberculosis can be made following the macroscopic
detection at necropsy of typical lesions. Histo-pathological examination of the lesion may …

Recent international developments in the area of infectious disease control and nontariff
trade barriers, along with possible zoonotic concerns, have provoked a revival of interest in …

ContextIdentifying persons with latent tuberculosis infection (LTBI) is crucial to the goal of TB
elimination. A whole-blood interferon γ (IFN-γ) assay, the QuantiFERON-TB test, is a …

BOVIGAMTMwhich is based on the detection of gamma interferon (IFN-γ) is a rapid,
laboratory assay of a cell mediated immune response that may be used for the detection of …

The currently available and accurate diagnostic tests for paratuberculosis are reviewed.
Technical issues concerning test performance are briefly mentioned and the advantages …

The strategic use of the gamma-interferon (IFN-γ) assay (Bovigam®) can provide a means
for the early identification of Mycobacterium bovis infected cattle, thus ensuring their removal …

Tuberculosis continues to be an important disease both in humans and animals. It causes
morbidity, mortality, and economic loss worldwide. The occurrence of Mycobacterium bovis …