Emerging evidence indicates that the detection and clearance of cancer cells via
phagocytosis induced by innate immune checkpoints play significant roles in tumor …

Cancers are a group of heterogeneous diseases characterized by the acquisition of
functional capabilities during the transition from a normal to a neoplastic state. Powerful …

Use of immunotherapy in recent years has revolutionized cancer treatment for certain types
of cancers. However, the broad utility of immunotherapy is limited because there are still …

GPR84 is a unique orphan G protein-coupled receptor (GPCR) that can be activated by
endogenous medium-chain fatty acids (MCFAs). The signaling of GPR84 is largely pro …

Targeting the anti-tumor immune response via the B7 family of immune-regulatory
checkpoint proteins has revolutionized cancer treatment and resulted in punctuated …

Abstract Radium‐223 (223Ra) is the first‐in‐class alpha‐emitter to mediate tumor
eradication, which is commonly thought to kill tumor cells by directly cleaving double‐strand …

Simple Summary The surrounding cells of the tumor tissue are called microenvironment,
and they may contribute to disease progression and/or antitumor immune response. Much …

Classic Hodgkin lymphoma (cHL) is characterized by a tumor microenvironment (TME)
containing inflammatory/immune cells. Follicular lymphoma, mediastinal gray zone …

Phagocytosis, a vital defense mechanism, involves the recognition and elimination of foreign
substances by cells. Phagocytes, such as neutrophils and macrophages, rapidly respond to …

In the treatment of relapsed or refractory multiple myeloma patients, BCMA-directed
autologous CAR-T cells have showed excellent anti-tumor activity. However, their …