The functional significance of velocity storage and its dependence on gravity

J Laurens, DE Angelaki - Experimental brain research, 2011 - Springer
Research in the vestibular field has revealed the existence of a central process, called
'velocity storage', that is activated by both visual and vestibular rotation cues and is modified …

The brain compass: a perspective on how self-motion updates the head direction cell attractor

J Laurens, DE Angelaki - Neuron, 2018 - cell.com
Head direction cells form an internal compass signaling head azimuth orientation even
without visual landmarks. This property is generated by a neuronal ring attractor that is …

Characteristics and mechanism of apogeotropic central positional nystagmus

JY Choi, S Glasauer, JH Kim, DS Zee, JS Kim - Brain, 2018 - academic.oup.com
Here we characterize persistent apogeotropic type of central positional nystagmus, and
compare it with the apogeotropic nystagmus of benign paroxysmal positional vertigo …

A unified internal model theory to resolve the paradox of active versus passive self-motion sensation

J Laurens, DE Angelaki - Elife, 2017 - elifesciences.org
Brainstem and cerebellar neurons implement an internal model to accurately estimate self-
motion during externally generated ('passive') movements. However, these neurons show …

Computation of linear acceleration through an internal model in the macaque cerebellum

J Laurens, H Meng, DE Angelaki - Nature neuroscience, 2013 - nature.com
A combination of theory and behavioral findings support a role for internal models in the
resolution of sensory ambiguities and sensorimotor processing. Although the cerebellum …

The otolith vermis: a systems neuroscience theory of the Nodulus and Uvula

J Laurens - Frontiers in Systems Neuroscience, 2022 - frontiersin.org
The Nodulus and Uvula (NU)(lobules X and IX of the cerebellar vermis) form a prominent
center of vestibular information processing. Over decades, fundamental and clinical …

Central positional nystagmus: characteristics and model-based explanations

JY Choi, JS Kim - Progress in Brain Research, 2019 - Elsevier
The central vestibular system operates to precisely estimate the rotational velocity and
gravity orientation using the inherently ambiguous information from peripheral vestibular …

Simple spike dynamics of Purkinje cells in the macaque vestibulo-cerebellum during passive whole-body self-motion

J Laurens, DE Angelaki - Proceedings of the National …, 2020 - National Acad Sciences
Theories of cerebellar functions posit that the cerebellum implements internal models for
online correction of motor actions and sensory estimation. As an example of such …

Cerebellum estimates the sensory state of the body

DJ Herzfeld, R Shadmehr - Trends in cognitive sciences, 2014 - cell.com
A recent neurophysiology study provides data from the cerebellar vermis/nodulus, where
neurons encode translation of the head, even when these translations are induced via an …

Modeling the effect of gravity on periodic alternating nystagmus

AA Shemesh, K Kocoglu, G Akdal, RT Ala… - Journal of the …, 2022 - Elsevier
Periodic alternating nystagmus (PAN) is a rare oscillatory ocular motor disorder. The effects
of gravity on the dynamic behavior of PAN can be studied by monitoring the nystagmus …