Correlation and association analyses in microbiome study integrating multiomics in health and disease

Y Xia - Progress in molecular biology and translational …, 2020 - Elsevier
Correlation and association analyses are one of the most widely used statistical methods in
research fields, including microbiome and integrative multiomics studies. Correlation and …

A deep learning pipeline for cross-sectional and longitudinal multiview data integration

S Jain, SE Safo - arXiv preprint arXiv:2312.01238, 2023 - arxiv.org
Biomedical research now commonly integrates diverse data types or views from the same
individuals to better understand the pathobiology of complex diseases, but the challenge …

LISA2: learning complex single-cell trajectory and expression trends

Y Chen, Y Zhang, JYH Li, Z Ouyang - Frontiers in Genetics, 2021 - frontiersin.org
Single-cell transcriptional and epigenomics profiles have been applied in a variety of tissues
and diseases for discovering new cell types, differentiation trajectories, and gene regulatory …

PATH: An interactive web platform for analysis of time-course high-dimensional genomic data

Y Zhang, Y Chen, Z Ouyang - International journal of …, 2020 - inderscienceonline.com
Discovering patterns in time-course genomic data can provide insights on the dynamics of
biological systems in health and disease. Here, we present a Platform for Analysis of Time …

Lagged principal trend analysis for longitudinal high‐dimensional data

Y Zhang - Stat, 2019 - Wiley Online Library
Biological systems are dynamic in nature, where time‐lagged correlations are commonly
observed. Motivated by the problem of integrating longitudinal high‐dimensional datasets …

Principal wave analysis for high-dimensional structured data with applications to epigenomics and neuroimaging studies

Y Zhang - Statistics and Its Interface, 2022 - intlpress.com
High-dimensional structured data are emerging and accumulating in biomedical research
fields. Examples include epigenomics and neuroimaging studies. In these studies, it is often …