Desmosomal cadherins are a recent evolutionary innovation that make up the adhesive core
of highly specialized intercellular junctions called desmosomes. Desmosomal cadherins …

Members of the ezrin–radixin–moesin (ERM) family of proteins are involved in multiple
aspects of cell migration by acting both as crosslinkers between the membrane, receptors …

The desmosomal cadherin desmoglein-1 (DSG1) is an essential intercellular adhesion
molecule that is altered in various human cutaneous disorders; however, its regulation and …

Disruption of cell adhesion plays a central role in dedifferentiation, invasion, and metastasis
of various cancers. The desmosome and hemidesmosome are anchoring junctions that …

Cancer metastasis is the primary cause of morbidity and mortality in cancer as it remains the
most complicated, devastating, and enigmatic aspect of cancer. Several decades of …

Lung adenocarcinoma (LADC) and squamous cell carcinoma (LSCC) are the most common
non-small cell lung cancer histological phenotypes. Accurate diagnosis distinguishing …

It is well recognized that the presence of cervical lymph node metastasis is the most
important prognostic factor in oral squamous cell carcinoma (OSCC). In solid epithelial …

Cervical cancer (CC) is a common gynecological malignancy. Despite the current screening
methods have been proved effectively and significantly decreased CC morbidity and …

Cell aggregation is frequently impaired during the growth of primary tumors and the
formation of metastatic lesions. Cell aggregation depends on cell–cell adhesion; however …

The Hippo pathway is an evolutionarily conserved pathway that serves to promote cell death
and differentiation while inhibiting cellular proliferation across species. The downstream …