[HTML][HTML] Artificial intelligence for COVID-19 drug discovery and vaccine development
SARS-COV-2 has roused the scientific community with a call to action to combat the growing
pandemic. At the time of this writing, there are as yet no novel antiviral agents or approved …
pandemic. At the time of this writing, there are as yet no novel antiviral agents or approved …
A review on drug repurposing applicable to COVID-19
S Dotolo, A Marabotti, A Facchiano… - Briefings in …, 2021 - academic.oup.com
Drug repurposing involves the identification of new applications for existing drugs at a lower
cost and in a shorter time. There are different computational drug-repurposing strategies and …
cost and in a shorter time. There are different computational drug-repurposing strategies and …
Lessons from the COVID-19 pandemic for advancing computational drug repurposing strategies
Responding quickly to unknown pathogens is crucial to stop uncontrolled spread of
diseases that lead to epidemics, such as the novel coronavirus, and to keep protective …
diseases that lead to epidemics, such as the novel coronavirus, and to keep protective …
A cross-talk between epithelium and endothelium mediates human alveolar–capillary injury during SARS-CoV-2 infection
P Wang, R Luo, M Zhang, Y Wang, T Song, T Tao… - Cell death & …, 2020 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, is an acute and rapidly developing pandemic,
which leads to a global health crisis. SARS-CoV-2 primarily attacks human alveoli and …
which leads to a global health crisis. SARS-CoV-2 primarily attacks human alveoli and …
Drug repurposing for COVID-19: A review and a novel strategy to identify new targets and potential drug candidates
L Rodrigues, R Bento Cunha, T Vassilevskaia… - Molecules, 2022 - mdpi.com
In December 2019, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), the causative agent of coronavirus disease 2019 (COVID-19) was first identified in the …
2), the causative agent of coronavirus disease 2019 (COVID-19) was first identified in the …
Data, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing
As the COVID-19 pandemic continues to spread, thousands of scientists around the globe
have changed research direction to understand better how the virus works and to find out …
have changed research direction to understand better how the virus works and to find out …
Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …
SARS-CoV-2 ORF9c is a membrane-associated protein that suppresses antiviral responses in cells
Disrupted antiviral immune responses are associated with severe COVID-19, the disease
caused by SAR-CoV-2. Here, we show that the 73-amino-acid protein encoded by ORF9c of …
caused by SAR-CoV-2. Here, we show that the 73-amino-acid protein encoded by ORF9c of …
COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms
We need to effectively combine the knowledge from surging literature with complex datasets
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …
Protein‐protein interaction networks as miners of biological discovery
Protein‐protein interactions (PPIs) form the basis of a myriad of biological pathways and
mechanism, such as the formation of protein complexes or the components of signaling …
mechanism, such as the formation of protein complexes or the components of signaling …