What roles do mesolimbic and neostriatal dopamine systems play in reward? Do they
mediate the hedonic impact of rewarding stimuli? Do they mediate hedonic reward learning …

Drug addiction can be conceptualized as a disturbance of behavior motivated by drug-
conditioned incentives. This abnormality has been explained by Incentive-Sensitization and …

While it has previously been assumed that mesolimbic dopamine neurons carry a reward
signal, recent data from single-unit, microdialysis and voltammetry studies suggest that …

Although the Skinnerian 'Empirical Law of Effect'does not directly consider the fundamental
properties of stimuli that enable them to act as reinforcers, such considerations are critical for …

An important aspect of motivated behavior is that organisms will perform complex
instrumental behaviors to gain access to stimuli such as food. In the present study, food …

Natural rewards preferentially stimulate dopamine transmission in the nucleus accumbens
shell. This effect undergoes adaptive changes (one-trial habituation, inhibition by appetitive …

How we decide whether a course of action is worth undertaking is largely unknown.
Recently, neuroscientists have been turning to ecological approaches to address this issue …

Background and objectives The idea that nucleus accumbens (Acb) dopamine transmission
contributes to the neural mediation of reward, at least in a general sense, has achieved wide …

In light of evidence implicating dopamine in the pathophysiology of attention deficit disorder
and schizophrenia, diseases involving attentional or sensory processing abnormalities, it …

Rationale Although tasks assessing the role of dopamine in effort-reward decisions are
similar to those concerned with the role of serotonin in impulsive choice in that both require …