The clinical relevance of gene expression based prognostic signatures in colorectal cancer
Colorectal cancer (CRC) is one of the most prevalent cancers, with more than one million
new cases every year. In the last few decades, several advancements in therapeutic and …
new cases every year. In the last few decades, several advancements in therapeutic and …
Multi-omics approaches in colorectal cancer screening and diagnosis, recent updates and future perspectives
I Ullah, L Yang, FT Yin, Y Sun, XH Li, J Li, XJ Wang - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is one of the most prevalent cancers worldwide.
Due to the absence of specific early symptoms, most of CRC patients are often diagnosed at …
Due to the absence of specific early symptoms, most of CRC patients are often diagnosed at …
A DNA methylation signature for the prediction of tumour recurrence in stage II colorectal cancer
M Li, C Zhu, Y Xue, C Miao, R He, W Li… - British Journal of …, 2023 - nature.com
Background A major challenge in stage II colorectal carcinoma is to identify patients with
increased risk of recurrence. Biomarkers that distinguish patients with poor prognosis from …
increased risk of recurrence. Biomarkers that distinguish patients with poor prognosis from …
Identification of dipeptidyl peptidase (DPP) family genes in clinical breast cancer patients via an integrated bioinformatics approach
Breast cancer is a heterogeneous disease involving complex interactions of biological
processes; thus, it is important to develop therapeutic biomarkers for treatment. Members of …
processes; thus, it is important to develop therapeutic biomarkers for treatment. Members of …
Natural killer cell-related prognosis signature predicts immune response in colon cancer patients
M Li, J Song, L Wang, Q Wang, Q Huang… - Frontiers in …, 2023 - frontiersin.org
Background: Natural killer (NK) cells are crucial components of the innate immune system
that fight tumors and viral infections. Patients with colorectal cancer (CRC) have a poor …
that fight tumors and viral infections. Patients with colorectal cancer (CRC) have a poor …
Comprehensive analysis of prognostic and genetic signatures for general transcription factor III (GTF3) in clinical colorectal cancer patients using bioinformatics …
Colorectal cancer (CRC) has the fourth-highest incidence of all cancer types, and its
incidence has steadily increased in the last decade. The general transcription factor III …
incidence has steadily increased in the last decade. The general transcription factor III …
Prognostic and therapeutic implications of extracellular matrix associated gene signature in renal clear cell carcinoma
Complex interactions in tumor microenvironment between ECM (extra-cellular matrix) and
cancer cell plays a central role in the generation of tumor supportive microenvironment. In …
cancer cell plays a central role in the generation of tumor supportive microenvironment. In …
DNA replication: Mechanisms and therapeutic interventions for diseases
HY Song, R Shen, H Mahasin, YN Guo, DG Wang - MedComm, 2023 - Wiley Online Library
Accurate and integral cellular DNA replication is modulated by multiple replication‐
associated proteins, which is fundamental to preserve genome stability. Furthermore …
associated proteins, which is fundamental to preserve genome stability. Furthermore …
Constructing a cancer stem cell related prognostic model for predicting immune landscape and drug sensitivity in colorectal cancer
J Chen, S Wu, Y Peng, Y Zhao, Y Dong… - Frontiers in …, 2023 - frontiersin.org
Background: Colorectal cancer (CRC) ranks the second malignancy with high incidence and
mortality worldwide. Cancer stem cells (CSCs) function critically in cancer progression and …
mortality worldwide. Cancer stem cells (CSCs) function critically in cancer progression and …
[HTML][HTML] Multi-platform-based characterization of ferroptosis in human colorectal cancer
Y Zhong, W Zhang, H Yu, L Lin, X Gao, J He, D Li… - Iscience, 2022 - cell.com
Ferroptosis is a type of programmed cell death potentially playing an important role in
colorectal cancer (CRC) development. However, comprehensive investigations toward …
colorectal cancer (CRC) development. However, comprehensive investigations toward …