The clinical relevance of gene expression based prognostic signatures in colorectal cancer

P Ahluwalia, R Kolhe, GK Gahlay - … et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
Colorectal cancer (CRC) is one of the most prevalent cancers, with more than one million
new cases every year. In the last few decades, several advancements in therapeutic and …

Multi-omics approaches in colorectal cancer screening and diagnosis, recent updates and future perspectives

I Ullah, L Yang, FT Yin, Y Sun, XH Li, J Li, XJ Wang - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is one of the most prevalent cancers worldwide.
Due to the absence of specific early symptoms, most of CRC patients are often diagnosed at …

A DNA methylation signature for the prediction of tumour recurrence in stage II colorectal cancer

M Li, C Zhu, Y Xue, C Miao, R He, W Li… - British Journal of …, 2023 - nature.com
Background A major challenge in stage II colorectal carcinoma is to identify patients with
increased risk of recurrence. Biomarkers that distinguish patients with poor prognosis from …

Identification of dipeptidyl peptidase (DPP) family genes in clinical breast cancer patients via an integrated bioinformatics approach

TK Choy, CY Wang, NN Phan, HD Khoa Ta, G Anuraga… - Diagnostics, 2021 - mdpi.com
Breast cancer is a heterogeneous disease involving complex interactions of biological
processes; thus, it is important to develop therapeutic biomarkers for treatment. Members of …

Natural killer cell-related prognosis signature predicts immune response in colon cancer patients

M Li, J Song, L Wang, Q Wang, Q Huang… - Frontiers in …, 2023 - frontiersin.org
Background: Natural killer (NK) cells are crucial components of the innate immune system
that fight tumors and viral infections. Patients with colorectal cancer (CRC) have a poor …

Comprehensive analysis of prognostic and genetic signatures for general transcription factor III (GTF3) in clinical colorectal cancer patients using bioinformatics …

G Anuraga, WC Tang, NN Phan, HDK Ta… - Current Issues in …, 2021 - mdpi.com
Colorectal cancer (CRC) has the fourth-highest incidence of all cancer types, and its
incidence has steadily increased in the last decade. The general transcription factor III …

Prognostic and therapeutic implications of extracellular matrix associated gene signature in renal clear cell carcinoma

P Ahluwalia, M Ahluwalia, AK Mondal, N Sahajpal… - Scientific reports, 2021 - nature.com
Complex interactions in tumor microenvironment between ECM (extra-cellular matrix) and
cancer cell plays a central role in the generation of tumor supportive microenvironment. In …

DNA replication: Mechanisms and therapeutic interventions for diseases

HY Song, R Shen, H Mahasin, YN Guo, DG Wang - MedComm, 2023 - Wiley Online Library
Accurate and integral cellular DNA replication is modulated by multiple replication‐
associated proteins, which is fundamental to preserve genome stability. Furthermore …

Constructing a cancer stem cell related prognostic model for predicting immune landscape and drug sensitivity in colorectal cancer

J Chen, S Wu, Y Peng, Y Zhao, Y Dong… - Frontiers in …, 2023 - frontiersin.org
Background: Colorectal cancer (CRC) ranks the second malignancy with high incidence and
mortality worldwide. Cancer stem cells (CSCs) function critically in cancer progression and …

[HTML][HTML] Multi-platform-based characterization of ferroptosis in human colorectal cancer

Y Zhong, W Zhang, H Yu, L Lin, X Gao, J He, D Li… - Iscience, 2022 - cell.com
Ferroptosis is a type of programmed cell death potentially playing an important role in
colorectal cancer (CRC) development. However, comprehensive investigations toward …