[HTML][HTML] The chemistry of snake venom and its medicinal potential

AL Oliveira, MF Viegas, SL da Silva… - Nature Reviews …, 2022 - nature.com
The fascination and fear of snakes dates back to time immemorial, with the first scientific
treatise on snakebite envenoming, the Brooklyn Medical Papyrus, dating from ancient Egypt …

Snake venom toxins: toxicity and medicinal applications

YS Chan, RCF Cheung, L Xia, JH Wong, TB Ng… - Applied microbiology …, 2016 - Springer
Snake venoms are complex mixtures of small molecules and peptides/proteins, and most of
them display certain kinds of bioactivities. They include neurotoxic, cytotoxic, cardiotoxic …

[HTML][HTML] An overview of the treatment of cutaneous leishmaniasis

TF Garza-Tovar, MI Sacriste-Hernández… - Faculty …, 2020 - ncbi.nlm.nih.gov
Leishmaniasis is a neglected tropical disease caused by species of Leishmania, with a
broad spectrum of clinical manifestations, such as cutaneous, visceral, and mucocutaneous …

Snake venom peptides and low mass proteins: molecular tools and therapeutic agents

JR Almeida, LM Resende, RK Watanabe… - Current medicinal …, 2017 - ingentaconnect.com
Snake venoms are natural sources of biologically active molecules that are able to act
selectively and specifically on different cellular targets, modulating physiological functions …

[HTML][HTML] Crotamine and crotalicidin, membrane active peptides from Crotalus durissus terrificus rattlesnake venom, and their structurally-minimized fragments for …

CB Falcao, G Radis-Baptista - Peptides, 2020 - Elsevier
A global public health crisis has emerged with the extensive dissemination of multidrug-
resistant microorganisms. Antimicrobial peptides (AMPs) from plants and animals have …

Investigating the cytotoxic effects of the venom proteome of two species of the Viperidae family (Cerastes cerastes and Cryptelytrops purpureomaculatus) from various …

CS Ozverel, M Damm, BF Hempel, B Göçmen… - … and Physiology Part C …, 2019 - Elsevier
Animal secretions are of great interest in terms of drug development due to their complex
protein and peptide composition. Especially, in the field of therapeutic medications such as …

Biological and Medical Aspects Related to South American Rattlesnake Crotalus durissus (Linnaeus, 1758): A View from Colombia

CA Cañas - Toxins, 2022 - mdpi.com
In Colombia, South America, there is a subspecies of the South American rattlesnake
Crotalus durissus, C. d. cumanensis, a snake of the Viperidae family, whose presence has …

Antiprotozoal effect of snake venoms and their fractions: A systematic review

ZU Abdullahi, SS Musa, D He, UM Bello - Pathogens, 2021 - mdpi.com
Background: Protozoal infection is a lingering public health issue of great concern, despite
efforts to produce drugs and vaccines against it. Recent breakthrough research has …

Acute toxicity, antinociceptive, and anti-inflammatory activities of the orally administered crotamine in mice

LA Moreira, LP Oliveira, MR Magalhães… - Naunyn-Schmiedeberg's …, 2021 - Springer
Crotamine is a polypeptide toxin isolated from rattlesnake venom. Although several studies
have been developed identifying many biological effects of isolated crotamine, none of them …

Quinine and chloroquine: Potential preclinical candidates for the treatment of tegumentary leishmaniasis

NRDLP Rossi, SN Fialho, A de Jesus Gouveia… - Acta Tropica, 2024 - Elsevier
Leishmaniasis is an endemic disease in more than 90 countries, constituting a relevant
public health problem. Limited treatment options, increase in resistance, and therapeutic …