The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN) 1, OCTN2,
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …

Ergothioneine (ERG) is an unusual thio-histidine betaine amino acid that has potent
antioxidant activities. It is synthesised by a variety of microbes, especially fungi (including in …

Farming and sedentism first appeared in southwestern Asia during the early Holocene and
later spread to neighboring regions, including Europe, along multiple dispersal routes …

This review describes current evidence supporting butyrate impact in the homeostatic
regulation of the digestive ecosystem in health and inflammatory bowel diseases (IBDs) …

Potential drug–drug interactions mediated by the ATP-binding cassette (ABC) transporter
and solute carrier (SLC) transporter families are of clinical and regulatory concern. However …

Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory disorder with an
unknown etiology. IBD is composed of two different disease entities: Crohn's disease (CD) …

Inflammatory bowel disease (IBD) results from a complex series of interactions between
susceptibility genes, the environment, and the immune system. The host microbiome, as well …

It is proposed that proteins/enzymes be classified into two classes according to their
essentiality for immediate survival/reproduction and their function in long-term health: that is …

There has been a recent surge of interest in the unique low molecular weight dietary
thiol/thione, ergothioneine. This compound can accumulate at high levels in the body from …

We sequenced Early Neolithic genomes from the Zagros region of Iran (eastern Fertile
Crescent), where some of the earliest evidence for farming is found, and identify a previously …