Snake venom three-finger α-neurotoxins (α-3FNTx) act on postsynaptic nicotinic
acetylcholine receptors (nAChRs) at the neuromuscular junction (NMJ) to produce skeletal …

Three‐finger fold toxins are miniproteins frequently found in Elapidae snake venoms. This
fold is characterized by three distinct loops rich in β‐strands and emerging from a dense …

Three-finger toxins (3FTx) represent one of the most abundantly secreted and potently toxic
components of colubrid (Colubridae), elapid (Elapidae) and psammophid (Psammophiinae …

Cardiovascular diseases such as coronary and peripheral artery diseases, venous
thrombosis, stroke, hypertension, and heart failure are enormous burden to health and …

We report the characterization, by combination of high-resolution on-line molecular mass
and disulfide bond profiling and top-down MS/MS analysis, of the venom proteomes of two …

The World Health Organization (WHO) recently added snakebite envenoming to the priority
list of Neglected Tropical Diseases (NTD). It is thought that~ 75% of mortality following …

Three-finger toxins (TFTs) comprise one of largest families of snake venom toxins. While
they are principal to and the most toxic components of the venoms of the Elapidae snake …

G protein-coupled receptors (GPCRs) represent important drug targets, as they regulate
pivotal physiological processes and they have proved to be readily druggable. Natural …

Cardiotoxins (CaTxs) are a group of snake toxins that affect the cardiovascular system
(CVS). Two types (S and P) of CaTxs are known, but the exact differences in the effects of …

Snake venoms, as complex mixtures of peptides and proteins, affect various vital systems of
the organism. One of the main targets of the toxic components from snake venoms is the …